Results 211 to 220 of about 2,265,568 (314)

The protein kinase Sch9 is a key regulator of sphingolipid metabolism inSaccharomyces cerevisiae

open access: green, 2013
Erwin Swinnen   +12 more
openalex   +2 more sources

Protein kinase CK2 impact on intracellular calcium homeostasis in prostate cancer

open access: green, 2020
Muhammad Afzal   +4 more
openalex   +2 more sources

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

open access: yesFEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel   +9 more
wiley   +1 more source

G Protein Coupled Receptor Kinase 3 Regulates Breast Cancer Migration, Invasion, and Metastasis

open access: gold, 2016
Matthew J. Billard   +13 more
openalex   +2 more sources

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

open access: yesFEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee   +3 more
wiley   +1 more source

Intermittent pH changes suggest acceleration of the extracellular signal-regulated kinase 1/2 (ERK1/2) mitogen-activated protein kinase (MAPK) and phosphatidylinositol-3 kinase (PI3K)/ protein kinase B (AKT) pathways.

open access: green
Ryota Nishida (22258400)   +10 more
openalex   +1 more source

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