Results 231 to 240 of about 2,265,568 (314)

Arecoline inhibits the growth of 3T3-L1 preadipocytes via AMP-activated protein kinase and reactive oxygen species pathways

, 2018
Zi-Han Tian, Jueng-Tsueng Weng, Li‐Jane Shih, An-Ci Siao, Tsai-Yun Chan, Yi-Wei Tsuei, Yow-Chii Kuo, Tsu-Shing Wang, Yung-Hsi Kao   +8 more
openalex   +2 more sources

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Knockdown of Serine-Arginine Protein Kinase 3 Impairs Sperm Development in <i>Spodoptera frugiperda</i>. [PDF]

Insects
Song Y, Zhou Y, Wang R, Zhang B, Li Z, Liu X, Li D.   +6 more
europepmc   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer. [PDF]

Oncol Rep
Leung RC, Liu SS, Chan KY, Tam KF, Chan KL, Wong LC, Ngan HY.   +6 more
europepmc   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

Protein kinase GIα oxidation negatively regulates antibody production by B cells. [PDF]

Redox Biol
Cho HJ, Charles RL, Prysyazhna O, Arjun S, Francois AA, McBride KM, Eaton P.   +6 more
europepmc   +1 more source

Acroamine A, a 2-Amino Adenine Alkaloid from the Marine Soft Coral Acrozoanthus australiae and Its Semisynthetic Derivatives That Inhibit cAMP-Dependent Protein Kinase A Catalytic Subunit Alpha

Sarath P. D. Senadeera, Dongdong Wang, Brice A. P. Wilson, Emily A. Smith, Antony Wamiru, Juliana A. Martinez Fiesco, Lin Du, Ping Zhang, Barry R. O’Keefe, John A. Beutler   +9 more
openalex   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Protein kinase C and endothelial dysfunction in select vascular diseases. [PDF]

Front Cardiovasc Med
Kant S, Feng J.
europepmc   +1 more source