Results 241 to 250 of about 4,965,955 (309)

Research progress of small molecule protein kinase inhibitors (SMKIs) in the treatment of colorectal cancer: mechanism, application, and future prospects. [PDF]

Front Pharmacol
Liu L, Chen Y, Guo M, Yun F, Li X, Lu C, Li Y, Li F.   +7 more
europepmc   +1 more source

Mitochondria‐Targeted Nanotherapies in Aging Neurodegenerative Disorders: Emerging Prospects and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave, Ashish B. Jadhav, Nitin B. Waghamode, Shubham Khot, Rajiya Khan, Ravi Hole, Shankar M. Dhobale, Manoj Aswar, Keshav Raj Paudel   +8 more
wiley   +1 more source

Host Protein Kinase C⍺: The novel Mitogen Activated Protein Kinase (MAPK) specific scaffold regulating nuclear export of influenza virus ribonucleoprotein complexes. [PDF]

PLoS Pathog
Das Jana I, Dey S, Si M, Roy A, Mondal A.   +4 more
europepmc   +1 more source

From Cell‐Derived Vesicles to Hybrid Nanovectors: Biological Membranes as Functional Blueprints for Gene Delivery

Advanced Healthcare Materials, EarlyView.
Biologically derived and hybrid nonviral nanovectors are examined as distinct but convergent design approaches. Integrating synthetic components with biologically functionalized membranes allows efficient interactions with complex cellular environments.
Clara Baldari, Claudia Leone, Gabriella Leccese, Claudia De Stradis, Alessandra Invidia, Concetta Quintarelli, Biagio De Angelis, Franco Locatelli, Giuseppe Gigli, Gabriele Maiorano, Ilaria Elena Palamà   +10 more
wiley   +1 more source

Blood–Brain Barrier Regulation: Evolving From Classic Strategies to Electrochemical Ion and Reactive Oxygen Species Control

Advanced Healthcare Materials, EarlyView.
Conventional therapies suffer from poor blood–brain barrier (BBB) penetration and disordered ion/reactive oxygen species (ROS) homeostasis, hindering precise neurological treatment. Electrochemical strategies achieve accurate spatiotemporal regulation of neural homeostasis.
Xiaokang Hu, Caiyu Liu, Meijun Pang, Zhiyuan Shi, Dong Ming, Xiuyun Liu   +5 more
wiley   +1 more source

[Retracted] Homeobox B9 facilitates hypertrophic scar formation via activating the mitogen‑activated protein kinase signaling pathway. [PDF]

Mol Med Rep
Xie Q, Liu D, Yu M, Wu X, Zhao Y, Hu Q, Wang Q.   +6 more
europepmc   +1 more source

An inhibitor of GCN2 and the integrated stress response directly targets ZAK protein kinase to limit cytotoxicity. [PDF]

J Biol Chem
Misra J, Spandau DF, Vilseck JZ, Anthony TG, Staschke KA, Wek RC.   +5 more
europepmc   +1 more source

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer. [PDF]

Oncol Rep
Leung RC, Liu SS, Chan KY, Tam KF, Chan KL, Wong LC, Ngan HY.   +6 more
europepmc   +1 more source

Cerebellar hypoplasia caused by calcium/calmodulin-dependent serine protein kinase deficiency. [PDF]

Mol Cells
Tabuchi K, Kouyama-Suzuki E, Yanagawa T, Shirai Y.   +3 more
europepmc   +1 more source

Correction for You et al., p53-dependent inhibition of FKHRL1 in response to DNA damage through protein kinase SGK1. [PDF]

Proc Natl Acad Sci U S A
europepmc   +1 more source