Results 21 to 30 of about 5,942,738 (437)

A-kinase-anchoring proteins [PDF]

open access: yesJournal of Cell Science, 2004
Highly organized molecular complexes determine the precise location and timing of the signal transduction events that occur downstream of cell surface receptor activation ([Pawson and Nash, 2003][1]). One set of scaffolding molecules that organize such complexes is a family of proteins known as A-
John D. Scott, Lorene K. Langeberg
openaire   +4 more sources

A-Kinase Anchoring Proteins in Cardiac Myocytes and Their Roles in Regulating Calcium Cycling

open access: yesCells, 2023
The rate of calcium cycling and calcium transient amplitude are critical determinants for the efficient contraction and relaxation of the heart. Calcium-handling proteins in the cardiac myocyte are altered in heart failure, and restoring the proper ...
Hariharan Subramanian   +1 more
doaj   +1 more source

Oxidant Sensing by Protein Kinases A and G Enables Integration of Cell Redox State with Phosphoregulation

open access: yesSensors, 2010
The control of vascular smooth muscle contractility enables regulation of blood pressure, which is paramount in physiological adaptation to environmental challenges.
Joseph R. Burgoyne, Philip Eaton
doaj   +1 more source

Identification of sites phosphorylated by the vaccinia virus B1R kinase in viral protein H5R [PDF]

open access: yes, 2000
Background: Vaccinia virus gene B1R encodes a erine/threonine protein kinase. In vitro this protein kinase phosphorylates ribosomal proteins Sa and S2 and vaccinia virus protein H5R, proteins that become phosphorylated during infection.
Beaud, G.   +4 more
core   +3 more sources

Metabolic Kinases Moonlighting as Protein Kinases [PDF]

open access: yesTrends in Biochemical Sciences, 2018
Protein kinases regulate every aspect of cellular activity, whereas metabolic enzymes are responsible for energy production and catabolic and anabolic processes. Emerging evidence demonstrates that some metabolic enzymes, such as pyruvate kinase M2 (PKM2), phosphoglycerate kinase 1 (PGK1), ketohexokinase (KHK) isoform A (KHK-A), hexokinase (HK), and ...
Zhimin Lu, Zhimin Lu, Tony Hunter
openaire   +2 more sources

Protein Kinase C [PDF]

open access: yesIUBMB Life, 2000
Phosphorylation is a universal language used by cells to relay information between and within cells. One family of kinases that plays a key role in transducing information is the protein kinase C family. Members of this family interpret information from signals that result in phospholipid hydrolysis; they communicate to substrates throughout the cell ...
openaire   +3 more sources

Label-Free Assay of Protein Kinase A Activity and Inhibition Using a Peptide-Based Electrochemical Sensor

open access: yesBiomedicines, 2021
We propose a simple label-free electrochemical biosensor for monitoring protein kinase activity and inhibition using a peptide-modified electrode. The biosensor employs cys-kemptide (CLRRASLG) as a substrate peptide which was immobilized on the surface ...
Hyunju Cho, Chang-Seuk Lee, Tae Hyun Kim
doaj   +1 more source

A guanosine 5′-triphosphate-dependent protein kinase is localized in the outer envelope membrane of pea chloroplasts [PDF]

open access: yes, 1988
A guanosine 5-triphosphate (GTP)-dependent protein kinase was detected in preparations of outer chloroplast envelope membranes of pea (Pisum sativum L.) chloroplasts.
A.M. Edelman   +34 more
core   +1 more source

Secreted protein kinases [PDF]

open access: yesTrends in Biochemical Sciences, 2013
Protein kinases constitute one of the largest gene families and control many aspects of cellular life. In retrospect, the first indication for their existence was reported 130 years ago when the secreted protein, casein, was shown to contain phosphate.
Jack E. Dixon   +3 more
openaire   +4 more sources

A plant homologue to mammalian brain 14-3-3 protein and protein kinase C inhibitor [PDF]

open access: yes, 1992
We have isolated cDNA clones of Spinacea oleracea L. and Oenothera hookeri of 930 and 1017 base pairs, respectively. The open reading frame deduced from the Oenothera sequence codes for a protein of a calculated molecular mass of 29 200.
Aitken   +16 more
core   +1 more source

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