Results 11 to 20 of about 2,106,225 (315)
The Ca2+/Calmodulin-dependent Protein Kinase Kinases Are AMP-activated Protein Kinase Kinases [PDF]
Journal of Biological Chemistry, 2005 The AMP-activated protein kinase (AMPK) is an important regulator of cellular metabolism in response to metabolic stress and to other regulatory signals. AMPK activity is absolutely dependent upon phosphorylation of AMPKalphaThr-172 in its activation loop by one or more AMPK kinases (AMPKKs).
Rebecca L, Hurley +5 more
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A-kinase-anchoring proteins [PDF]
Journal of Cell Science, 2004 Highly organized molecular complexes determine the precise location and timing of the signal transduction events that occur downstream of cell surface receptor activation ([Pawson and Nash, 2003][1]). One set of scaffolding molecules that organize such complexes is a family of proteins known as A-
Lorene K, Langeberg, John D, Scott
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Physiological Phosphorylation of Protein Kinase A at Thr-197 Is by a Protein Kinase A Kinase [PDF]
Molecular and Cellular Biology, 1998 Phosphorylation of the catalytic subunit of cyclic AMP-dependent protein kinase, or protein kinase A, on Thr-197 is required for optimal enzyme activity, and enzyme isolated from either animal sources or bacterial expression strains is found phosphorylated at this site.
R D, Cauthron +3 more
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Protein Kinases in Leukemias [PDF]
Cancers, 2021 Protein kinases (PK) make up around 2% of the human genome and their expression profile varies depending on the organ and tissue [...]
Paulo De Sepulveda, Jean-Max Pasquet
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The concentration of androgen receptor and protein kinase A in male chicken following the administration of a combination of the epididymis and testicular extracts [PDF]
Veterinary World, 2020 Background and Aim: Testis (T) and epididymis (E) are waste from the abattoir that is rarely used. In fact, both organs contain important chemicals needed for spermatogenesis (e.g., hormones, proteins, and other molecules). Therefore, administration of a
Muslim Akmal +6 more
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Correlation of human protein kinase A (PKA) and G-glycoprotein in patients with T2DM
Medical Journal of Babylon, 2021 Background: Type 2 diabetes usually starts with insulin resistance—a condition that happens when muscle, fat, and liver cells cannot use insulin to deliver glucose into the cells of the body for energy use.
Sura S Khadhim +2 more
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Protein Kinase A in Cancer [PDF]
Cancers, 2011 In the past, many chromosomal and genetic alterations have been examined as possible causes of cancer. However, some tumors do not display a clear molecular and/or genetic signature. Therefore, other cellular processes may be involved in carcinogenesis.
CARETTA A, MUCIGNAT, CARLA
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Metabolic Kinases Moonlighting as Protein Kinases [PDF]
Trends in Biochemical Sciences, 2018 Protein kinases regulate every aspect of cellular activity, whereas metabolic enzymes are responsible for energy production and catabolic and anabolic processes. Emerging evidence demonstrates that some metabolic enzymes, such as pyruvate kinase M2 (PKM2), phosphoglycerate kinase 1 (PGK1), ketohexokinase (KHK) isoform A (KHK-A), hexokinase (HK), and ...
Zhimin, Lu, Tony, Hunter
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Sensors, 2010 The control of vascular smooth muscle contractility enables regulation of blood pressure, which is paramount in physiological adaptation to environmental challenges.
Joseph R. Burgoyne, Philip Eaton
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A guanosine 5′-triphosphate-dependent protein kinase is localized in the outer envelope membrane of pea chloroplasts [PDF]
, 1988 A guanosine 5-triphosphate (GTP)-dependent protein kinase was detected in preparations of outer chloroplast envelope membranes of pea (Pisum sativum L.) chloroplasts.
A.M. Edelman +34 more
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