Results 161 to 170 of about 1,243,636 (309)

Protein kinase C-theta (PKCθ) phosphorylates and inhibits the guanine exchange factor, GIV/Girdin [PDF]

, 2013
Inmaculada López-Sánchez, Mikel Garcia‐Marcos, Yash Mittal, Nicolas Aznar, Marilyn G. Farquhar, Pradipta Ghosh   +5 more
openalex   +1 more source

Estradiol Triggers Cerebellar MLI-PC LTP via ERβ/Protein Kinase C Signaling Cascades in Mice In Vivo. [PDF]

Int J Mol Sci
Zhang ZY, Chen L, Sun MZ, Chen CY, Wang CY, Todo Y, Tang Z, Lv YC, Zou QY, Chu CP, Xu YH, Qiu DL.   +11 more
europepmc   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

A2B adenosine receptor-triggered intracellular calcium mobilization: Cell type-dependent involvement of Gi, Gq, Gs proteins and protein kinase C [PDF]

Zhan-Guo Gao, Ray R. Gao, Christina Meyer, Kenneth A. Jacobson   +3 more
openalex   +1 more source

A comparative study of the activation of protein kinase C α by different diacylglycerol isomers [PDF]

, 1999
Pilar Sánchez‐Piñera, Vicente Micol, Senena Corbalán-Garcı́a, Juan C. G. ÓMEZ-FERNÁNDEZ   +3 more
openalex   +1 more source

Critical role of the β isoform of protein kinase C (PKCβ) in angiotensin II-induced oxidative stress in vascular smooth muscle cells. [PDF]

Physiol Rep
Tajima H, Naganishi S, Mukohda M, Ishida M, Hamada N, Shigemi N, Yamasaki T, Nakamura S, Matsui T, Mizuno R, Ozaki H.   +10 more
europepmc   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Phosphorylation of Alzheimer disease amyloid precursor peptide by protein kinase C and Ca2+/calmodulin-dependent protein kinase II. [PDF]

, 1988
Sam Gandy, Andrew J. Czernik, Paul Greengard   +2 more
openalex   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

Adenosine A2A Receptor mRNA Regulation by Nerve Growth Factor Is TrkA-, Src-, and Ras-dependent via Extracellular Regulated Kinase and Stress-activated Protein Kinase/c-Jun NH2-terminal Kinase [PDF]

, 1999
Renae L. Malek, Zhongzhen Nie, Vickram Ramkumar, Norman H. Lee   +3 more
openalex   +1 more source