Results 221 to 230 of about 1,251,015 (259)
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Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2006
Protein kinase C (PKC) isozymes constitute a family of ubiquitous phosphotransferases which act as key transducers in many agonist-induced signaling cascades. To date, at least 11 different PKC isotypes have been identified and are believed to play distinct regulatory roles. PKC isoforms are physiologically activated by a number of lipid cofactors. PKC
MARTELLI, ALBERTO MARIA +3 more
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Protein kinase C (PKC) isozymes constitute a family of ubiquitous phosphotransferases which act as key transducers in many agonist-induced signaling cascades. To date, at least 11 different PKC isotypes have been identified and are believed to play distinct regulatory roles. PKC isoforms are physiologically activated by a number of lipid cofactors. PKC
MARTELLI, ALBERTO MARIA +3 more
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Regulation of protein kinase C
Current Opinion in Cell Biology, 1997Protein kinase C has been in the spotlight since the discovery two decades ago that it is activated by the lipid second messenger diacylglycerol. Despite protein kinase C's enduring stage presence, the regulation and specific roles of its isozymes in defined cellular processes are still under intense investigation.
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AGC protein kinase phosphorylation and protein kinase C
Biochemical Society Transactions, 2001Protein kinase cascades feature in many signal transduction pathways. For those discussed here, a single upstream protein kinase appears to be responsible for the control of multiple downstream targets. So how is specificity introduced into these events?
Parker, P J, Parkinson, S J
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Protein Kinase C Isotypes in C. elegans
Journal of Biochemistry, 2002The protein kinase C (PKC) family, consisting of multiple isotypes, plays a major role in cellular signaling. In the nematode Caenorhabditis elegans, four pkc genes, tpa-1, pkc-1, pkc-2 and pkc-3, have been identified and investigated. Molecular analysis of tpa-1, pkc-1, and pkc-2 has shown that each gene encodes multiple PKC isoforms with different ...
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Kinase-mediated RAS signaling via membraneless cytoplasmic protein granules
Cell, 2021Juan Guan, Jayanta Debnath, Siyu Feng
exaly
Protein Kinase C and Vasospasm
Journal of Neurosurgery, 1996T, Matsui, T, Asano
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Activation of the c-Raf protein kinase by protein kinase C phosphorylation.
Oncogene, 1992The product of the c-raf-1 proto-oncogene is a cytoplasmic serine/threonine protein kinase that appears to be activated in signal transduction from a variety of cell-surface receptors. The mechanism of c-Raf activation upon stimulation of cell-surface receptors is not clear, but there seem to exist multiple pathways of activation which involve tyrosine
O, Sözeri +6 more
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Nihon rinsho. Japanese journal of clinical medicine, 1995
Protein kinase C (PKC) is a phospholipid-dependent protein kinase that plays important roles in various cellular functions. At least 11 PKC isozymes are known, and structural differences classify these isozymes into three groups, conventional PKC (cPKC), novel PKC (nPKC) and atypical PKC (aPKC).
H, Matsushima, S, Shimohama
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Protein kinase C (PKC) is a phospholipid-dependent protein kinase that plays important roles in various cellular functions. At least 11 PKC isozymes are known, and structural differences classify these isozymes into three groups, conventional PKC (cPKC), novel PKC (nPKC) and atypical PKC (aPKC).
H, Matsushima, S, Shimohama
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