Results 231 to 240 of about 2,497,817 (373)

Activation of dsRNA-Dependent Protein Kinase R by miR-378 Sustains Metabolic Inflammation in Hepatic Insulin Resistance. [PDF]

Diabetes, 2021
Wang H, Song Y, Wu Y, Kumar V, Mahato RI, Su Q.   +5 more
europepmc   +1 more source

Porcine Reproductive and Respiratory Syndrome Virus Infection Induces Stress Granule Formation Depending on Protein Kinase R-like Endoplasmic Reticulum Kinase (PERK) in MARC-145 Cells [PDF]

, 2017
Yanrong Zhou, Liurong Fang, Dang Wang, Kaimei Cai, Huanchun Chen, Shaobo Xiao   +5 more
openalex   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Author Correction: VHS, US3 and UL13 viral tegument proteins are required for Herpes Simplex Virus-Induced modification of protein kinase R. [PDF]

Sci Rep, 2021
Pennisi R, Musarra-Pizzo M, Lei Z, Zhou GG, Sciortino MT.   +4 more
europepmc   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Activation of the Protein Kinase R-Like Endoplasmic Reticulum Kinase (PERK) Pathway of the Unfolded Protein Response after Experimental Traumatic Brain Injury and Treatment with a PERK Inhibitor. [PDF]

Neurotrauma Rep, 2021
Brady RD, Bird S, Sun M, Yamakawa GR, Major BP, Mychasiuk R, O'Brien TJ, McDonald SJ, Shultz SR.   +8 more
europepmc   +1 more source

Rapid adaptation to human protein kinase R by a unique genomic rearrangement in rhesus cytomegalovirus [PDF]

, 2020
Stephanie J. Child, Alexander L. Greninger, Adam P. Geballe   +2 more
openalex   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Essential role of protein kinase R in the pathogenesis of pulmonary veno-occlusive disease. [PDF]

JCI Insight
Prabhakar A, Kumar R, Wadhwa M, Barpanda A, Lyons J, Gowda A, Gupta S, Arvind A, Ghatpande P, Wiita AP, Graham BB, Lagna G, Hata A.   +12 more
europepmc   +1 more source

A pivotal role for protein kinase R in the oncostatin m and interleukin-1 induced catabolic phenotype in bovine articular cartilage chondrocytes

, 2009
Sophie Gilbert, Victor C. Duance, D.J. Mason   +2 more
openalex   +2 more sources