Results 261 to 270 of about 2,497,817 (373)

Host species-specific interactions of protein kinase R and poxvirus pseudosubstrate inhibitors

, 2016
Chen Peng
openalex   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Chandipura Virus Forms Cytoplasmic Inclusion Bodies through Phase Separation and Proviral Association of Cellular Protein Kinase R and Stress Granule Protein TIA-1. [PDF]

Viruses
Sarkar S, Ganguly S, Ganguly NK, Sarkar DP, Sharma NR.   +4 more
europepmc   +1 more source

SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas, Pablo Iruzubieta, Alberto Damborenea, Laura Pérez‐Fernández, Inmaculada Azorín, Juan Carlos Jiménez García, Ana Töpf, Pilar Martí, Lorena Fores‐Toribio, María Manterola, Rosana Blanco‐Mañez, Oihane Pikatza‐Menoio, Sonia Alonso‐Martín, Volker Straub, Aitziber L. Cortajarena, Adolfo López de Munain, David De Sancho, Lorea Blázquez, Juan J. Vilchez   +18 more
wiley   +1 more source

APOL1 risk allele RNA contributes to renal toxicity by activating protein kinase R

, 2018
Koji Okamoto, Jason W. Rausch, Hidefumi Wakashin, Yulong Fu, Joon‐Yong Chung, Patrick Dummer, Myung K. Shin, Preeti Chandra, Kosuke Suzuki, Shashi Shrivastav, Avi Z. Rosenberg, Stephen M. Hewitt, Patricio E. Ray, Eisei Noiri, Stuart F.J. Le Grice, Maarten Hoek, Zhe Han, Cheryl A. Winkler, Jeffrey B. Kopp   +18 more
openalex   +1 more source

Deciphering Protein Kinase Specificity Through Large-Scale Analysis of Yeast Phosphorylation Site Motifs

Science Signaling, 2010
J. Mok, Philip M. Kim, Hugo Y. K. Lam, Stacy Piccirillo, Xiuqiong Zhou, Grace R. Jeschke, D. Sheridan, Sirlester A. Parker, Ved Desai, M. Jwa, E. Cameroni, Hengyao Niu, Matthew C. Good, A. Reményi, Jia Ma, Yi-Jun Sheu, Holly E. Sassi, Richelle Sopko, Clarence S. M. Chan, C. De Virgilio, N. M. Hollingsworth, W. Lim, D. Stern, B. Stillman, B. Andrews, M. Gerstein, M. Snyder, B. Turk   +27 more
semanticscholar   +1 more source

Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan, John R. Mills, Paulina Vargas, Naveen K. Paramasivan, Connie E. Lesnick, Eati Basal, Surendra Dasari, James P. Fryer, Shannon R. Hinson, Joseph Laporta, Amy Espinal, Dennis Fitzgerald, Carolina Garcia, Anna E. Morenkova, Paola Pergami, Anna Shah, Andrew Knight, Reghann LaFrance Corey, Vanda A. Lennon, Anastasia Zekeridou, Sean J. Pittock, Divyanshu Dubey, Andrew McKeon   +22 more
wiley   +1 more source

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela, Madison Reeves, Karen Jansen‐West, Judith Dunmore, Yuping Song, Audrey Strongosky, Sunil Gandhi, Gilana Pikover, Matt Blurton‐Jones, Robert C. Spitale, Erik H. Middlebrooks, Leonard Petrucelli, Mercedes Prudencio, Zbigniew K. Wszolek   +13 more
wiley   +1 more source

Fasciola gigantica Recombinant Abelson Tyrosine Protein Kinase (rFgAbl) Regulates Various Functions of Buffalo Peripheral Blood Mononuclear Cells. [PDF]

Animals (Basel)
Zhao M, Zou Y, Chen W, Wu D, Xian C, Yang H, Tan J, Di W, Wu W, Wang D.   +9 more
europepmc   +1 more source

RNase L Amplifies Interferon Signaling by Inducing Protein Kinase R-Mediated Antiviral Stress Granules. [PDF]

J Virol, 2020
Manivannan P, Siddiqui MA, Malathi K.
europepmc   +1 more source