Results 181 to 190 of about 4,239,129 (300)

Protein phosphatase 2A/Hedgehog pathway governs efferocytosis of pulmonary macrophages and participates in nanoplastics-induced mouse lung injury. [PDF]

Cell Biol Toxicol
Zhang J, Zhang Y, Wen L, Li Z, Cai Y, Wan M, Li W, Zhu X, Pang Y, Li D, Chen S, Guo P, Wang Q, Chen W, Chen L.   +14 more
europepmc   +1 more source

Autophosphorylation of ataxia-telangiectasia mutated (ATM) is regulated by protein phosphatase 2A in vivo

, 2004
Ionizing radiation induces autophosphorylation of the ataxia-telangiectasia mutated (ATM) protein kinase on serine 1981; however, the precise mechanisms that regulate ATM activation are not fully understood.
Aaron Goodarzi (16046546), David Young (369006), Kum Kum Khanna (11619798), Greg BG Moorhead (16070150), Susan P Lees-Miller (16060760), Jyoti C Jonnalagadda (16070144), Pauline Douglas (15800309), Ye Ruiqiong (16070147)   +7 more
core  

Dephosphorylation of nNOS at Ser⁸⁴⁷ by protein phosphatase 2A [PDF]

FEBS Letters, 2001
Komeima, Keiichi, Watanabe, Yasuo
openaire   +2 more sources

Phase Separation of TRIM21 Modulates PTPN14 Stability to Drive Flow‐Dependent Endothelial Activation and Atherogenesis

Advanced Science, EarlyView.
Disturbed flow promotes the formation of TRIM21‐rich biomolecular droplets, which concentrate TRIM21 and PTPN14 and facilitate their SPRY‐FERM interaction (illustrated by the TRIM21 D355‐PTPN14 R132 salt bridge). This condensate‐driven proximity enables TRIM21 to catalyze K48‐linked polyubiquitination of PTPN14 at lysine 956, leading to proteasome ...
Xue He, Qiannan Ma, Xue Wang, Jiaxu Mang, Chufeng Li, Bingjun Wu, Liu Yao, Yequn Chen, Qiankun Bao, Yi Zhu, Jinlong He   +10 more
wiley   +1 more source

The tumor suppressor NDRG2 recruits protein phosphatase 2A to suppress STAT5 phosphorylation in adult T-cell leukemia/lymphoma. [PDF]

J Biol Chem
Ichikawa T, Nakahata S, Shimoda K, Murakami T, Morishita K.   +4 more
europepmc   +1 more source

Selective Modulation of OTUB1 Noncanonical Function via a bioPhosTAC Strategy

Advanced Science, EarlyView.
This work positions the versatile performance of the peptide‐based bioPhosTAC platform for dissecting phosphorylation‐dependent biology and expanding the scope of induced‐proximity technologies. We demonstrated that selective manipulation of a tyrosine phosphorylation site is sufficient to propagate coordinated cellular consequences.
Seung Un Seo, Seon Min Woo, Minhyeong Choi, Soeun Rhee, Simmyung Yook, Donghyuk Shin, Kwang‐Su Park, Taeg Kyu Kwon   +7 more
wiley   +1 more source

Protein phosphatase 2A subunit B55 alpha is required for angiotensin type 2 receptor elicited natriuresis. [PDF]

Am J Physiol Renal Physiol
Gildea JJ, Li J, Howell NL, Kemp BA, Conaway MR, Brautigan DL, Carey RM, Keller SR.   +7 more
europepmc   +1 more source

Protein phosphatase 2A: a high-value target of virulence factors. [PDF]

Trends Parasitol, 2023
Gohmann R, Mackey D.
europepmc   +1 more source

OsCPK12‐OsATPD1 Module Regulates Photosynthetic Acclimation to Light Stress in Rice

Advanced Science, EarlyView.
OsCPK12 interacts and phosphorylates OsAtpD1 at Ser8 in its transit peptide. This phosphorylation promote its chloroplast translocation, thereby maintaining ATP synthase activity and proton gradient (ΔpH) homeostasis and regulating photosynthetic acclimation, photoprotection, and repair under light stress.
Beifang Wang, Aaron Chan, Yongyi Fan, Yanwu Wang, Pao Xue, Yingxin Zhang, Xiaodeng Zhan, Weixun Wu, Ping Yu, Daibo Chen, Junlin Fu, Yongbo Hong, Xihong Shen, Lianping Sun, Aike Zhu, Shihua Cheng, Qunen Liu, Liyong Cao   +17 more
wiley   +1 more source

Beyond IC₅₀: Reframing Microcystin Potency against Protein Phosphatase 2A by Defining Two-Step Irreversible Inhibition Kinetics. [PDF]

ACS Omega
Hummel KN, Stringer BB, Thenuwara SI, Westrick JA, Kodanko JJ.   +4 more
europepmc   +1 more source