Results 261 to 270 of about 4,194,516 (299)
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11 Reversible methylation of protein phosphatase 2A
2006PP2A has been shown to be methylated at the C-terminal leucine residue of the catalytic subunit by a specific 38 kDa methyltransferase (LCMT1) and demethylated by a specific 44-kDa methylesterase (PME-1). This reversible methylation does not seem to drastically change the PP2A activity but is shown to be a modulating factor in the binding of the third ...
Sari, Longin, Jozef, Goris
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Regulation of protein kinase cascades by protein phosphatase 2A
Trends in Biochemical Sciences, 1999Many protein kinases themselves are regulated by reversible phosphorylation. Upon cell stimulation, specific kinases are transiently phosphorylated and activated. Several of these protein kinases are substrates for protein phosphatase 2A (PP2A), and PP2A appears to be the major kinase phosphatase in eukaryotic cells that downregulates activated protein
Millward TA, Zolnierowicz S, Hemmings BA
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Dephosphorylation of cardiac myofibril C-protein by protein phosphatase 1 and protein phosphatase 2A
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1987C-protein purified from chicken cardiac myofibrils was phosphorylated with the catalytic subunit of cAMP-dependent protein kinase to nearly 3 mol [32P]phosphate/mol C protein. Digestion of 32P-labeled C-protein with trypsin revealed that the radioactivity was nearly equally distributed in three tryptic peptides which were separated by reversed-phase ...
K K, Schlender +2 more
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Regulation of Recombinant PKCα Activity by Protein Phosphatase 1 and Protein Phosphatase 2A
Archives of Biochemistry and Biophysics, 1998The sensitivity of PKC alpha to two protein phosphatases (PP1 and PP2A) has been studied. The results show that both phosphatases reversibly inhibit PKC alpha activity suggesting an effect at PKC autophosphorylation sites and not at transphosphorylation sites.
RICCIARELLI, ROBERTA, AZZI A.
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Targeting Protein Phosphatases in Cancer Immunotherapy and Autoimmune Disorders
Nature Reviews Drug Discovery, 2023Nunzio Bottini, Stephanie M Stanford
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Protein Phosphatase 2A and Protein Phosphatase X Genes in Arabidopsis thaliana
1998G, Pujol, A, Ferrer, J, Ariño
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Plant Protein Phosphatases: What Do We Know About Their Mechanism of Action?
FEBS Journal, 2021Swati Mahiwal +2 more
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Prostatic Acid Phosphatase: Where Are We?
Ca-A Cancer Journal for Clinicians, 1978T M Chu, G P Murphy
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