Expression of prion protein in mouse erythroid progenitors and differentiating murine erythroleukemia cells. [PDF]
Prion diseases have been observed to deregulate the transcription of erythroid genes, and prion protein knockout mice have demonstrated a diminished response to experimental anemia.
Martin Panigaj +3 more
doaj +1 more source
A morphological view on mitochondrial protein targeting [PDF]
Mitochondrial protein targeting includes both intramitochondrial sorting of proteins encoded by the organellar genome and import and subsequent sorting of nuclear encoded precursor proteins. Only a few proteins are encoded by the mitochondrial genome and
Ida J. van der Klei +5 more
core +1 more source
Neuroprotective Secreted Amyloid Precursor Protein Acts by Disrupting Amyloid Precursor Protein Dimers [PDF]
The amyloid precursor protein (APP) is implied both in cell growth and differentiation and in neurodegenerative processes in Alzheimer disease. Regulated proteolysis of APP generates biologically active fragments such as the neuroprotective secreted ectodomain sAPPalpha and the neurotoxic beta-amyloid peptide.
Gralle, Matthias +2 more
openaire +5 more sources
Protein translocation across mitochondrial membranes [PDF]
Protein translocation across biological membranes is of fundamental importance for the biogenesis of organelles and in protein secretion. We will give an overview of the recent achievements in the understanding of protein translocation across ...
Walter Neupert +3 more
core +1 more source
Structural transitions during large ribosomal subunit maturation analyzed by tethered nuclease structure probing in S. cerevisiae. [PDF]
Yeast large ribosomal subunit (LSU) precursors are subject to substantial changes in protein composition during their maturation due to coordinated transient interactions with a large number of ribosome biogenesis factors and due to the assembly of ...
Gisela Pöll +8 more
doaj +1 more source
Rrp47p is an exosome-associated protein required for the 3 ' processing of stable RNAs [PDF]
Related exosome complexes of 3'-->5' exonucleases are present in the nucleus and the cytoplasm. Purification of exosome complexes from whole-cell lysates identified a Mg2+-labile factor present in substoichiometric amounts. This protein was identified
Tollervey, D +4 more
core +1 more source
Import pathways of precursor proteins into mitochondria [PDF]
The precursor of porin, a mitochondrial outer membrane protein, competes for the import of precursors destined for the three other mitochondrial compartments, including the Fe/S protein of the bc1- complex (intermembrane space), the ADP/ATP carrier ...
Pfaller, Rupert +4 more
core +1 more source
The protein import apparatus of chloroplasts [PDF]
Routing of cytosolically synthesized precursor proteins into chloroplasts is a specific process which involves a multitude of soluble and membrane components.
Soll, Jürgen +3 more
core +1 more source
The significant influence of residual feed intake on flavor precursors and biomolecules in slow-growing Korat chicken meat [PDF]
Objective This study investigated the association between feed efficiency, physicochemical properties, flavor precursors and biomolecules in the thigh meat of Korat (KR) chickens.
Chotima Poompramun +3 more
doaj +1 more source
Congenital Dyserythropoietic Anemia Type II: molecular analysis and expression of the
Background Congenital dyserythropoietic anemia type II (CDAII), the most common form of CDA, is an autosomal recessive condition. CDAII diagnosis is based on invasive, expensive, and time consuming tests that are available only in specialized ...
Punzo Francesca +9 more
doaj +1 more source

