Медицинская иммунология, 2014 We studied the effect of a recombinant murine TNF (rmTNF) and TNF-binding protein of Variola virus (VARV-CrmB) upon colony-forming ability of bone marrow cells (BMC) from Balb/c mice.
L. B. Toporkova +3 more
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Amyloid precursor protein and amyloid precursor-like protein 2 in cancer
Oncotarget, 2016 Amyloid precursor protein (APP) and its family members amyloid precursor-like protein 1 (APLP1) and amyloid precursor-like protein 2 (APLP2) are type 1 transmembrane glycoproteins that are highly conserved across species. The transcriptional regulation of APP and APLP2 is similar but not identical, and the cleavage of both proteins is regulated by ...
Pandey, Poomy +11 more
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ENTAIL: yEt aNoTher amyloid fIbrils cLassifier
BMC Bioinformatics, 2022 Background This research aims to increase our knowledge of amyloidoses. These disorders cause incorrect protein folding, affecting protein functionality (on structure).
Alessia Auriemma Citarella +3 more
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Computer-aided characteristics of proteins as potential precursors of bioactive peptides
Polimery, 2003 Proteins, apart from their basic functions, may play the role of precursors of the peptides that regulate the body functions and/or show antihypertensive, antithrombotic, antiamnestic, immunomodulating and other activities. Computer analysis of 109
Jerzy Dziuba
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PLoS ONE, 2019 Many of the small ribosomal subunit proteins are required for the stabilisation of late small ribosomal subunit (SSU) precursors and for final SSU rRNA processing in S. cerevisiae.
Jan Linnemann +6 more
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Expression of prion protein in mouse erythroid progenitors and differentiating murine erythroleukemia cells. [PDF]
PLoS ONE, 2011 Prion diseases have been observed to deregulate the transcription of erythroid genes, and prion protein knockout mice have demonstrated a diminished response to experimental anemia.
Martin Panigaj +3 more
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ELOVL4 protein preferentially elongates 20:5n3 to very long chain PUFAs over 20:4n6 and 22:6n3
Journal of Lipid Research, 2012 We hypothesized that reduction/loss of very long chain PUFAs (VLC-PUFAs) due to mutations in the ELOngase of very long chain fatty acid-4 (ELOVL4) protein contributes to retinal degeneration in autosomal dominant Stargardt-like macular dystrophy (STGD3 ...
Man Yu +6 more
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Structural transitions during large ribosomal subunit maturation analyzed by tethered nuclease structure probing in S. cerevisiae. [PDF]
PLoS ONE, 2017 Yeast large ribosomal subunit (LSU) precursors are subject to substantial changes in protein composition during their maturation due to coordinated transient interactions with a large number of ribosome biogenesis factors and due to the assembly of ...
Gisela Pöll +8 more
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Neuroprotective Secreted Amyloid Precursor Protein Acts by Disrupting Amyloid Precursor Protein Dimers [PDF]
Journal of Biological Chemistry, 2009 The amyloid precursor protein (APP) is implied both in cell growth and differentiation and in neurodegenerative processes in Alzheimer disease. Regulated proteolysis of APP generates biologically active fragments such as the neuroprotective secreted ectodomain sAPPalpha and the neurotoxic beta-amyloid peptide.
Gralle, M. ; https://orcid.org/0000-0002-0472-4263 +2 more
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The significant influence of residual feed intake on flavor precursors and biomolecules in slow-growing Korat chicken meat [PDF]
Animal Bioscience, 2021 Objective This study investigated the association between feed efficiency, physicochemical properties, flavor precursors and biomolecules in the thigh meat of Korat (KR) chickens.
Chotima Poompramun +3 more
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