Results 31 to 40 of about 3,910,498 (310)

Hsp90 Breaks the Deadlock of the Hsp70 Chaperone System [PDF]

, 2018
Protein folding in the cell requires ATP-driven chaperone machines such as the conserved Hsp70 and Hsp90. It is enigmatic how these machines fold proteins.
Mayer, Matthias, Sub Cellular Protein Chemistry, Kityk, R., Rüdiger, S.G.D., Morán Luengo, T., Cellular Protein Chemistry   +5 more
core   +2 more sources

Targeting apoptotic anticancer response with natural glucosinolates from cell suspension culture of Lepidium sativum

Journal of Genetic Engineering and Biotechnology, 2023
Background Finding natural products with anticancer activity is an effective strategy to fight this disease. In this respect, Lepidium sativum or garden cress (family Brassicaceae) has been widely used worldwide for its wide therapeutic application ...
Mona M. Ibrahim, Marwa M. Mounier, Shawky A. Bekheet   +2 more
doaj   +1 more source

Expressed protein ligation for a large dimeric protein [PDF]

, 2011
Expressed protein ligation (EPL) is a protein engineering tool for post-translational ligation of protein or peptide fragments. This technique allows modification of specific parts of proteins, opening possibilities for incorporating probes for ...
NMR Spectroscopy, Karagöz, G.E., Sub Cellular Protein Chemistry, O. Hsieh, Sub NMR Spectroscopy, T. Sinnige, Rüdiger, S.G.D., Hsieh, O., Sinnige, T, G. E. Karagoz, S. G. D. Rudiger, Cellular Protein Chemistry   +11 more
core   +1 more source

Precursor Protein for Newcastle Disease Virus [PDF]

Journal of Virology, 1973
The course of viral protein synthesis during infection of chicken embryo fibroblasts with Newcastle disease virus (NDV) L. Kansas has been followed by using sodium dodecyl sulfate polyacrylamide gel electrophoresis. Of the three major virion polypeptide molecular weight classes, I (78,400 daltons), II (53,500 daltons), and III (37,600 daltons), only II,
A C, Samson, C F, Fox
openaire   +2 more sources

Pyramidalization of the Glycosidic Nitrogen Provides the Way for Efficient Cleavage of the N‑Glycosidic Bond of 8‑OxoG with the hOGG1 DNA Repair Protein [PDF]

, 2012
A mechanistic pathway for cleavage of the N-glycosidic bond of 8-oxo-2′-deoxyguanosine (oxoG) catalyzed with the human 8-oxoguanine glycosylase 1 DNA repair protein (hOGG1) is proposed in this theoretical study. The reaction scheme suggests direct proton
Sychrovský, V., Sub Cellular Protein Chemistry, Sebera, J., Tanaka, Y., Trantirek, L., Cellular Protein Chemistry   +5 more
core   +1 more source

Amyloid precursor protein processing and bioenergetics [PDF]

Brain Research Bulletin, 2017
The processing of amyloid precursor protein (APP) to amyloid beta (Aβ) is of great interest to the Alzheimer's disease (AD) field. Decades of research define how APP is altered to form Aβ, and how Aβ generates oligomers, protofibrils, and fibrils. Numerous signaling pathways and changes in cell physiology are known to influence APP processing. Existing
Heather M. Wilkins, Russell H. Swerdlow
openaire   +2 more sources

Picky Hsp90-Every Game with Another Mate [PDF]

, 2017
In this issue of Molecular Cell, Sahasrabudhe et al. (2017) present a dramatically renovated functional cycle for the molecular chaperone Hsp90, which stimulates re-thinking of the mechanism of this vital protein folding ...
Sub Cellular Protein Chemistry, Rüdiger, Stefan G D, Radli, Martina, Cellular Protein Chemistry   +3 more
core   +2 more sources

Citrus psorosis virus 24K protein inhibits the processing of miRNA precursors by interacting with components of the biogenesis machinery

Microbiology Spectrum
Sweet orange (Citrus sinensis) is one of the most important fruit crops worldwide. Virus infections in this crop can interfere with cellular processes, causing dramatic economic losses. By performing RT-qPCR analyses, we demonstrated that citrus psorosis
Facundo E. Marmisolle, María B. Borniego, Damián A. Cambiagno, Lucia Gonzalo, María L. García, Pablo A. Manavella, Carmen Hernández, Carina A. Reyes   +7 more
doaj   +1 more source

Early emergence of ethnic differences in type 2 diabetes precursors in the UK: the Child Heart and Health Study in England (CHASE Study) [PDF]

, 2010
<p><b>Background:</b> Adults of South Asian origin living in the United Kingdom have high risks of type 2 diabetes and central obesity; raised circulating insulin, triglyceride, and C-reactive protein concentrations; and low HDL ...
Cook Derek G., Owen, C.G., Alberti, KG, Whincup, PH, Derek G Cook, Whincup, P.H., Rudnicka, A.R., K George M M Alberti, Sattar, N, Alicja R Rudnicka, Gibb Ian, Sattar, N., Gibb, I, Rudnicka Alicja R., McKay, CM, Nightingale, C.M., Sattar Naveed, McKay, C.M., Whincup Peter H., Ian Gibb, Donin, AS, Rudnicka, AR, Angela S Donin, Donin Angela S., Alberti K. George M. M., Gibb, I., Nightingale Claire M., Nightingale, CM, Catherine M McKay, Naveed Sattar, Cook, D.G., McKay Catherine M., Owen Christopher G., Owen, CG, Donin, A.S., Cook, DG, Claire M Nightingale, Alberti, K.G.M.M., Peter H Whincup, Christopher G Owen   +39 more
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MOM19, an import receptor for mitochondrial precursor proteins [PDF]

, 1989
We have identified a 19 kd protein of the mitochondrial outer membrane (MOM19). Monospecific IgG and Fab fragments directed against MOM19 inhibit import of precursor proteins destined for the various mitochondrial subcompartments, including porin ...
Söllner, Thomas, Pfaller, Rupert, Pfanner, Nikolaus, Neupert, Walter, Griffiths, Gareth   +4 more
core   +1 more source