Results 281 to 290 of about 508,657 (349)

Alpha-synuclein overexpression triggers divergent cellular responses and post-translational modifications in SH-SY5Y and ReNcell VM models. [PDF]

Cell Mol Life Sci
Momand MUD, Majerova P, Mjartinova D, Maruskinova N, Albertusova K, Dobrota M, Fialova L, Stefankova S, Podlesniy P, Muhammadi MK, Balaz M, Fricova D.   +11 more
europepmc   +1 more source

Tuning the Testicular Microenvironment for Enhancing Human Sertoli Cells Maturation and Functionality In Vitro

Advanced Healthcare Materials, EarlyView.
An in vitro testicular model is developed by generating connective tissue equivalents from human dermal fibroblast‐derived microtissues and coupling them with human Sertoli cells or human Sertoli cell spheroids. This engineered microenvironment supports Sertoli cell maturation and functionality, providing a promising platform for studying human ...
Annachiara Scalzone, Giorgia Imparato, Chiara Ausilio, Valentina Mollo, Paolo Antonio Netti   +4 more
wiley   +1 more source

Molecular mechanisms involved in <i>Plasmodium</i> gametocytogenesis. [PDF]

Front Microbiol
Scovino AM, Oliveira-da-Silva RS, Almeida-da-Silva J, Mendes KD, da Silva-Junior EB, Decote-Ricardo D, Freire-de-Lima L, Freire-de-Lima CG, Totino PRR, Morrot A.   +9 more
europepmc   +1 more source

Packed for Ossification: High‐Density Bioprinting of hPDC Spheroids in HAMA Toward Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
Human periosteum‐derived cell spheroids bioprinted at high density within a hyaluronic acid matrix promote fusion and hypertrophic cartilage formation in vitro. Early encapsulation enhances spheroid interaction and matrix maturation, generating scalable cartilage templates intended for endochondral bone regeneration.
Ane Albillos Sanchez, Maria Paula Marks, Paula Casademunt, Adrián Seijas‐Gamardo, Ioannis Papantoniou, Lorenzo Moroni, Carlos Mota   +6 more
wiley   +1 more source

Antigen anisotropy: The overlooked geometric determinant of vaccine immunogenicity and fidelity. [PDF]

Hum Vaccin Immunother
Santiago D.
europepmc   +1 more source

CORE: Cholesterol Altered Lipid Nanoparticles for Splenic Expression of mRNA Payloads

Advanced Healthcare Materials, EarlyView.
In this paper researchers introduce CORE LNPs, a new class of lipid nanoparticles engineered to redirect mRNA expression away from the liver and into the spleen, a key immune organ. By combining chemical design with computational tools, they created cholesterol analogs that enable precise spleen‐targeted expression, providing greater applications for ...
Eshan A. Narasipura, Vincent Fung, Rachel VanKeulen‐Miller, Palas B. Tiwade, Owen S. Fenton   +4 more
wiley   +1 more source

Reshaping cancer cell plasticity by P-body dynamics and protein translation. [PDF]

Commun Biol
Senatore E, Rinaldi L, Chiuso F, Bianco AG, Feliciello A.   +4 more
europepmc   +1 more source

Dynamic lysine acetylation and succinylation of platelet proteins regulates platelet storage lesion: mechanistic insights from multi-omics. [PDF]

Ann Med
Liao X, Zhang C, Chen M, Zhou J, Luo X, Zhang Y, Hu X, Wang Z, Wang L.   +8 more
europepmc   +1 more source

GID/CTLH E3 ligase complex control cell fate programs for sexual development of Plasmodium falciparum. [PDF]

Nat Commun
Marapana DS, Lopaticki S, Balan B, Reaksudsan K, Cobbold SA, Geoghegan ND, Khurana S, Scally SW, Hickey P, Jayakrishnan N, Vaibhav V, Spall S, Yousef JM, Dagley LF, Goodman CD, Cozijnsen A, McFadden GI, Rogers KL, Jex A, Komander D, McCarthy JS, Tonkin CJ, Dixon MWA, Cowman AF.   +23 more
europepmc   +1 more source

Decoding chemerin proteolytic processing and isoform signaling across disease contexts. [PDF]

iScience
Wang J, Deng J, Xiao T, Meng W.
europepmc   +1 more source