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RNA N4-acetylcytidine modification in human cancers: from molecular function to oncogenic mechanisms. [PDF]
iScienceShi Y, Sun J, Chen H, Yu K, Li J, Liu B.
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The post-translational processing of ras p21 is critical for its stimulation of mitogen-activated protein kinaseopenaire
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The role of post-translational modification in beta-amyloid precursor protein processing.
Biochemical Society Symposia, 2001The ϐ-amyloid precursor protein (APP) plays a pivotal role in the early stages of neurodegeneration associated with Alzheimer's disease. An alteration in the processing pattern of the protein results in an increase in the generation of the 40-42-amino-acid ϐ-amyloid (Aϐ) peptide, which coalesces to form insoluble, extracellular amyloid deposits.
N. Georgopoulou +3 more
semanticscholar +3 more sources
Effect of triethyllead on post-translational processing of myelin proteins
Experimental Neurology, 1982Abstract The effect of triethyllead (PbEt3) on entry of newly synthesized proteins into myelin was studied in an in vitro system of brain stem slices prepared from actively myelinating young rats. The slices were incubated 30 min with [3H]leucine then the labeling of proteins was halted by a chase with cold amino acid and the slices were incubated an
G, Konat, H, Offner
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Journal of Chromatography A, 1995
It has been demonstrated that good agreement may be observed between computed and experimental isoelectric point (pI) values when proteins of known sequence are focused under denaturing conditions on immobilized pH gradient IPG slabs, at least in the pH range 4-7.5.
Elisabetta Gianazza
semanticscholar +4 more sources
It has been demonstrated that good agreement may be observed between computed and experimental isoelectric point (pI) values when proteins of known sequence are focused under denaturing conditions on immobilized pH gradient IPG slabs, at least in the pH range 4-7.5.
Elisabetta Gianazza
semanticscholar +4 more sources
Post-translational processing of 7S and 11S components of soybean storage proteins
Plant Molecular Biology, 1981The synthesis and processing of the major storage proteins in soybean cotyledons was studied both in vivo and in vitro. The α and α' subunits of 7S as well as the 11S proteins are synthesized as higher molecular weight-precursors on membrane-bound polysomes.
C, Sengupta +3 more
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Journal of Immunology, 1992
Maturation of blood monocytes into macrophages is accompanied by a number of functional changes including decreased IL-1 beta release in response to LPS. This limitation has previously been ascribed to transcriptional regulation.
D. Herzyk +3 more
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Maturation of blood monocytes into macrophages is accompanied by a number of functional changes including decreased IL-1 beta release in response to LPS. This limitation has previously been ascribed to transcriptional regulation.
D. Herzyk +3 more
semanticscholar +1 more source
Journal of Pharmaceutical and Biomedical Analysis, 2020
Because the increasing morbidity of pertussis in all age groups worldwide, the quality of pertussis vaccines has aroused a common concern. To improve the quality of pertussis vaccine in research and production, the effects of manufacture processes on post-translational modifications (PTMs) of bioactive proteins in pertussis vaccine were investigated by
Zhen, Long +8 more
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Because the increasing morbidity of pertussis in all age groups worldwide, the quality of pertussis vaccines has aroused a common concern. To improve the quality of pertussis vaccine in research and production, the effects of manufacture processes on post-translational modifications (PTMs) of bioactive proteins in pertussis vaccine were investigated by
Zhen, Long +8 more
openaire +2 more sources