Results 301 to 310 of about 508,657 (349)
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SYNTHESIS AND POST-TRANSLATIONAL PROCESSING OF SURFACTANT PROTEIN C
Pediatric Pathology & Molecular Medicine, 2001Traditional thinking about surfactant proteins has centered around their effects on the biophysical properties of surfactant phospholipids. Accumulated data now suggests that the four major surfactant proteins (SPs) are a biochemically and functionally diverse group of mammalian peptides that have function beyond modification of alveolar surface ...
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Impact of post-translational modifications of proteins on the inflammatory process
Biochemical Society Transactions, 2007PTM (post-translational modification) is the chemical modification of a protein after its translation. The well-studied PTM is phosphorylation, but, recently, PTMs have been re-focused by extensive studies on histone modifications and the discovery of the ubiquitin system.
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Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1989
Surfactant proteolipid SP-B is a hydrophobic protein of Mr = 8000 identified in organic solvent extracts of pulmonary surfactant. Analysis of the human SP-B RNA predicts that the active surfactant peptide is derived by proteolysis of an Mr = 40,000 precursor.
M A, O'Reilly +5 more
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Surfactant proteolipid SP-B is a hydrophobic protein of Mr = 8000 identified in organic solvent extracts of pulmonary surfactant. Analysis of the human SP-B RNA predicts that the active surfactant peptide is derived by proteolysis of an Mr = 40,000 precursor.
M A, O'Reilly +5 more
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Clinica Chimica Acta, 2017
Basic research is showing new mechanisms involved in early immune responses and Neutrophil Extracellular Trap (NET) formation (or NETosis) is of key importance as first line defense against bacteria, virus and protozoa. Enzymatic modification of arginine in citrulline in histones is the prerequisite of NETosis being it necessary for decondensation and ...
Bruschi, Maurizio +9 more
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Basic research is showing new mechanisms involved in early immune responses and Neutrophil Extracellular Trap (NET) formation (or NETosis) is of key importance as first line defense against bacteria, virus and protozoa. Enzymatic modification of arginine in citrulline in histones is the prerequisite of NETosis being it necessary for decondensation and ...
Bruschi, Maurizio +9 more
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Post-Translational Processing of Surfactant Protein-C Proprotein
American Journal of Respiratory Cell and Molecular Biology, 2001Rat surfactant protein (SP)-C is a 3.7-kD hydrophobic lung-specific protein generated from proteolytic processing of a 21-kD propeptide (SP-C(21)). We have demonstrated that initial post-translational processing of SP-C(21) involves two cleavages of the COOH-terminus (Beers and colleagues, J. Biol. Chem. 1994;269:20,318--20,328).
A L, Johnson +6 more
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Post-translational Proteolytic Processing on Intracellular Proteins by Cathepsins and Cystatins
2010Post-translational proteolytic modification by limited proteolysis is not only a biological process that produces biologically active proteins (peptides), but because almost all intracellular biologically active proteins are synthesized as pre-pro forms, ordered limited proteolysis by specific proteases is an essential process.
Nobuhiko Katunuma +2 more
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Synthesis and post-translational processing of surfactant protein C.
Pediatric pathology & molecular medicine, 2002Traditional thinking about surfactant proteins has centered around their effects on the biophysical properties of surfactant phospholipids. Accumulated data now suggests that the four major surfactant proteins (SPs) are a biochemically and functionally diverse group of mammalian peptides that have function beyond modification of alveolar surface ...
K O, Solarin, W J, Wang, M F, Beers
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Protein Transport and Post-translational Processing in Photosystem II Biosynthesis and Homeostasis
2005The biogenesis, repair and homeostasis of Photosystem II (PS II) requires both protein targeting and post-translational modification. The various chloroplast targeting pathways for both nuclear-encoded and chloroplast-encoded proteins are described, with emphasis on the subunits of PS II.
Steven M. Theg, Lan-Xin Shi
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Engineering Post-Translational Processing of Recombinant Proteins Produced in Insect Cell Culture
2000A number of host organisms are used today to facilitate the production of recombinant proteins. Recombinant proteins are produced in cultures derived from both prokaryotic and eukaryotic sources. The proteins obtained from these sources are used in a wide range of applications including diagnostics, structure-function studies, therapeutics, and ...
E. Ailor, M. J. Betenbaugh
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Post-translational processing in the synthesis of egg-specific protein in the silkworm, Bombyx mori
Insect Biochemistry, 1989Abstract The post-translational processing of egg-specific protein (ESP) in developing ovarian follicles of the silkworm, Bombyx mori was analyzed using in vivo and in vitro labeling systems with some radioactive precursors. The labeling with[ 35 S]methionine revealed that ESP is first synthesized as 69 kDa peptide (69K-ESP) which is then ...
Yukihiro Sato, Okitsugu Yamashita
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