Results 21 to 30 of about 11,534,197 (263)
A Computational Model of the LGI1 Protein Suggests a Common Binding Site for ADAM Proteins [PDF]
Mutations of human leucine-rich glioma inactivated (LGI1) gene encoding the epitempin protein cause autosomal dominant temporal lateral epilepsy (ADTLE), a rare familial partial epileptic syndrome.
Leonardi, Emanuela +23 more
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Background Despite advances in treatment of patients with non-small cell lung cancer, carriers of certain genetic alterations are prone to failure. One such factor frequently mutated, is the tumor suppressor PTEN.
Thomas Fischer +16 more
doaj +1 more source
We separated a novel functional peptide IFPPKPKDTL from porcine plasma hydrolysate by chromatography, HPLC, and identified by Q Exactive LC-MS/MS. Results showed that IFPPKPKDTL had a significant ability of ACE inhibition (76.6%) likely due to the ...
Junqi Zhan +3 more
doaj +1 more source
Alzheimer Cells on Their Way to Derailment Show Selective Changes in Protein Quality Control Network [PDF]
Alzheimer’s Disease is driven by protein aggregation and is characterized by accumulation of Tau protein into neurofibrillary tangles. In healthy neurons the cellular protein quality control is successfully in charge of protein folding, which raises the ...
Rüdiger, Stefan G.D. +1 more
core +3 more sources
Molecular mechanism of Asi- mediated protein quality control [PDF]
Misfolded proteins in the membrane and lumen of the endoplasmic reticulum (ER) are eliminated by a quality control system called ER-associated protein degradation (ERAD).
Natarajan, Nivedita
core +1 more source
Charactering the spoilage mechanism of “three sticks” of Jinhua ham
To investigate the spoilage characteristics of Jinhua ham, sensory scores, volatile compounds, biogenic amine, physicochemical parameters and microbial counts were evaluated between normal and spoiled hams.
Changyu Zhou +6 more
doaj +1 more source
: This study developed and characterized a γ-aminobutyric acid (GABA)-enriched yogurt fermented by Levilactobacillus brevis CGMCC1.5954. The GABA content in the yogurt was 147.36 mg/100 mL, which was 317.06% higher than that of the control group ...
Xiankang Fan +6 more
doaj +1 more source
Ubiquitin-proteasome dependent mitochondrial protein quality control [PDF]
Dysfunctional mitochondria cause many neurodegenerative disorders and with aging in general, mechanisms of mitochondrial quality control are essential for cellular function.
Benischke, Anne-Sophie
core +1 more source
In this study, a functionalized mesoporous silica-coated solid-phase microextraction (SPME) Arrow system was developed for the enrichment of six biogenic amines (BAs) from pork and fish samples before gas chromatographic separation with a mass ...
Mengfei Chen +3 more
doaj +1 more source
CHAPTER 1.1. Disulfide Bonds in Protein Folding and Stability [PDF]
Disulfide bonds are unique among post-translational modifications, as they add covalent crosslinks to the polypeptide chain. Accordingly, they can exert pronounced effects on protein folding and stability. This is of particular importance for secreted or
Sub Cellular Protein Chemistry +7 more
core +1 more source

