Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Proposed interpretation of quality control standards : documentation of compliance with a system of quality control;Documentation of compliance with a system of quality control; Exposure draft (American Institute of Certified Public Accountants), 1982, Feb. 8 [PDF]
The proposed interpretation is to advise CPA firms that documentation would ordinarily be required to demonstrate a firms\u27s compliance with its quality control policies and procedures.https://egrove.olemiss.edu/aicpa_sop/1440/thumbnail ...
American Institute of Certified Public Accountants. Quality Control Standards Committee
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Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Commentary: PROTACs make undruggable targets druggable: Challenge and opportunity
Bin Lu, Jianpin Ye
doaj +1 more source
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
T.O.T.A.L Quality Control Yang sukses
Buku ini membahas tentang total quality control, materi pembahasannya yaitu: memahami pengertian, prinsip dan manfaat total quality control; analisa kebutuhan perubahan dalam organisasi; melakukan assesmen dalam organisasi; perencanaan perubahan ...
John Macdonald
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A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Extension and adoption of biofortified crops: Quality protein maize in East Africa [PDF]
Biofortified crops, bred for improved nutritional quality, can alleviate nutritional deficiencies if they are produced and consumed in sufficient quantities.
De Groote, Hugo +3 more
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Supplementary materials for "Loss of protein synthesis quality control in host-restricted organisms"
This are the supplementary data for the PNAS publication entitled "Loss of protein synthesis quality control in obligate intracellular parasites"
Sergey Melnikov (5929346)
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