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Protein Quality Control in Cardiomyocytes
2012Protein quality control (PQC) plays an indispensable role in maintaining protein homeostasis in cardiomyocytes. PQC is a fundamental cellular process, whose role it is to sense and repair misfolded/unfolded proteins and, if the repair fails, degrade the terminally misfolded polypeptides through an intricate collaboration between molecular chaperones ...
Xuejun Wang, Cam Patterson
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Quality control: ER-associated degradation: protein quality control and beyond.
The Journal of cell biology, 2014Even with the assistance of many cellular factors, a significant fraction of newly synthesized proteins ends up misfolded. Cells evolved protein quality control systems to ensure that these potentially toxic species are detected and eliminated. The best characterized of these pathways, the ER-associated protein degradation (ERAD), monitors the folding ...
Annamaria, Ruggiano +2 more
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Cancer treatment and survivorship statistics, 2022
Ca-A Cancer Journal for Clinicians, 2022Kimberly D Miller +2 more
exaly
Cervical cancer prevention and control in women living with human immunodeficiency virus
Ca-A Cancer Journal for Clinicians, 2021Philip E Castle, Vikrant V Sahasrabuddhe
exaly
Sweetening protein quality control
Nature Reviews Molecular Cell Biology, 2014openaire +1 more source
Quality control of protein drugs.
Arzneimittel-Forschung, 1988Testing of protein drugs must include assays for purity, identity, safety, and potency. The structure of the final product as well as potential impurities are strongly influenced by the type of producing organism (bacteria, yeast, mammalian or insect cells).
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Cancer statistics in China, 2015
Ca-A Cancer Journal for Clinicians, 2016Rongshou Zheng +2 more
exaly