Results 281 to 290 of about 22,982,554 (304)

Protein quality control by the proteasome and autophagy: A regulatory role of ubiquitin and liquid-liquid phase separation.

Matrix Biology, 2020
Degradation of dysfunctional, damaged, or misfolded proteins is a crucial component of the protein quality control network to maintain cellular proteostasis.
Lin-Lin Lei, Zhi-Xiao Wu, K. Winklhofer
semanticscholar   +1 more source

Potential benefit of manipulating protein quality control systems in neurodegenerative diseases.

Current Opinion in Neurobiology, 2020
The deposition of proteins of abnormal conformation is one of the major hallmarks of the common neurodegenerative diseases including Alzheimer's, Parkinson's, amyotrophic lateral sclerosis, frontotemporal dementia, and prion diseases.
L. Luh, A. Bertolotti
semanticscholar   +1 more source

The intersection of exercise and aging on mitochondrial protein quality control.

Experimental Gerontology, 2020
Skeletal muscle quality and quantity are negatively impacted with age. Part of this decline in function can be attributed to alterations in mitochondrial turnover, and in the mechanisms that regulate mitochondrial homeostasis.
Yuan Zhang, Ashley N. Oliveira, D. Hood
semanticscholar   +1 more source

Protein Quality Control Degradation in the Nucleus.

Annual Review of Biochemistry, 2018
Nuclear proteins participate in diverse cellular processes, many of which are essential for cell survival and viability. To maintain optimal nuclear physiology, the cell employs the ubiquitin-proteasome system to eliminate damaged and misfolded proteins ...
Charisma Enam, Yifat Geffen, T. Ravid, Richard G. Gardner   +3 more
semanticscholar   +1 more source

Time to Add Screening for Financial Hardship as a Quality Measure?

Ca-A Cancer Journal for Clinicians, 2021
Ya-Chen Tina Shih, Cathy J Bradley, Syed Yousuf Zafar   +2 more
exaly  

Glycosylation-Directed Quality Control of Protein Folding

Nature Reviews Molecular Cell Biology, 2015
Davis T W Ng
exaly  

Cancer Quality Alliance: Blueprint for a Better Cancer Care System

Ca-A Cancer Journal for Clinicians, 2008
Patricia A. Ganz
exaly  

Piecing Together Protein Quality Control

Nature Reviews Molecular Cell Biology, 2014
Katharine Wrighton
exaly  

Quality in Cancer Diagnosis

Ca-A Cancer Journal for Clinicians, 2010
Dana M Grzybicki, Stephen S Raab
exaly  

Mechanisms and Functions of Spatial Protein Quality Control.

Annual Review of Biochemistry, 2017
E. Sontag, Rahul S. Samant, J. Frydman
semanticscholar   +1 more source