Results 111 to 120 of about 6,885 (176)

Stress-induced protein S-glutathionylation in Arabidopsis

, 2005
S-Glutathionylation (thiolation) is a ubiquitous redox-sensitive and reversible modification of protein cysteinyl residues that can directly regulate their activity.
Edwards, R., Dixon, D.P., Grundy, N.M., Skipsey, M.   +3 more
core   +1 more source

Protein S-glutathionylation in HEK 293 cells.

, 2013
(A) The pattern of overall S-glutathionylated proteins is shown in a time course experiment with 0.5 mM diamide or 0.5 mM hydrogen peroxide-treated HEK 293 cells.
Yuh-Cherng Chai (375282), Jasen Lee Gilge (375281), Michael Fisher (25505)   +2 more
core   +1 more source

Additional file 3 of New insights into posttranslational modifications of proteins during bull sperm capacitation

, 2023
Additional file 2. Figure S2. Positive and negative control of 1D S-glutathionylation analysis. 1D gel analysis of relative fluorescence intensity corresponding to the levels of protein S-glutathionylation of bull sperm with negative and positive ...
Anna Janta (15269042), Anna Majewska (12506920), Agnieszka Mostek-Majewska (15269039), Andrzej Ciereszko (4993370)   +3 more
core   +1 more source

Chloroplasts lacking class I glutaredoxins are functional but show a delayed recovery of protein cysteinyl redox state after oxidative challenge

Redox Biology
Redox status of protein cysteinyl residues is mediated via glutathione (GSH)/glutaredoxin (GRX) and thioredoxin (TRX)-dependent redox cascades. An oxidative challenge can induce post-translational protein modifications on thiols, such as protein S ...
Finja Bohle, Jacopo Rossi, Sadia S. Tamanna, Hannah Jansohn, Marlene Schlosser, Frank Reinhardt, Alexa Brox, Stephanie Bethmann, Stanislav Kopriva, Oliver Trentmann, Peter Jahns, Marcel Deponte, Markus Schwarzländer, Paolo Trost, Mirko Zaffagnini, Andreas J. Meyer, Stefanie J. Müller-Schüssele   +16 more
doaj   +1 more source

Polysulfur-based bulking of dynamin-related protein 1 prevents ischemic sulfide catabolism and heart failure in mice

Nature Communications
The presence of redox-active molecules containing catenated sulfur atoms (supersulfides) in living organisms has led to a review of the concepts of redox biology and its translational strategy.
Akiyuki Nishimura, Seiryo Ogata, Xiaokang Tang, Kowit Hengphasatporn, Keitaro Umezawa, Makoto Sanbo, Masumi Hirabayashi, Yuri Kato, Yuko Ibuki, Yoshito Kumagai, Kenta Kobayashi, Yasunari Kanda, Yasuteru Urano, Yasuteru Shigeta, Takaaki Akaike, Motohiro Nishida   +15 more
doaj   +1 more source

The Thioredoxin-Regulated α-Amylase 3 of Arabidopsis thaliana Is a Target of S-Glutathionylation

Frontiers in Plant Science, 2019
Reactive oxygen species (ROS) are produced in cells as normal cellular metabolic by-products. ROS concentration is normally low, but it increases under stress conditions. To stand ROS exposure, organisms evolved series of responsive mechanisms.
Libero Gurrieri, Luca Distefano, Claudia Pirone, Daniel Horrer, David Seung, Mirko Zaffagnini, Nicolas Rouhier, Paolo Trost, Diana Santelia, Francesca Sparla   +9 more
doaj   +1 more source

Cigarette Smoke Targets Glutaredoxin 1, Increasing S-glutathionylation and Epithelial Cell Death

, 2011
It is established that cigarette smoke causes irreversible oxidations in lung epithelial cells and can lead to their death. However, its impact on reversible and physiologically relevant redox-dependent protein modifications remains to be investigated ...
Kuipers, I., Niki L. Reynaert, Reynaert, N.L., Emiel F. M. Wouters, Aesif, S.W., Freek G. Bouwman, Edwin C. Mariman, Amy S. Guala, Scott W. Aesif, Ine Kuipers, Konings, G.F.J., Yvonne M. W. Janssen-Heininger, Guala, A.S., Janssen Heininger, Y.M., Gonda Konings, Bouwman, F.G., Mariman, E.C., Wouters, E.F.M.   +17 more
core   +1 more source

Glutathione S-transferases interact with AMP-activated protein kinase: evidence for S-glutathionylation and activation in vitro.

PLoS ONE, 2013
AMP-activated protein kinase (AMPK) is a cellular and whole body energy sensor with manifold functions in regulating energy homeostasis, cell morphology and proliferation in health and disease.
Anna Klaus, Sarah Zorman, Alexandre Berthier, Cécile Polge, Sacnicte Ramirez, Sylvie Michelland, Michel Sève, Didier Vertommen, Mark Rider, Nicolas Lentze, Daniel Auerbach, Uwe Schlattner   +11 more
doaj   +1 more source

S-Glutathionylation in Monocyte and Macrophage (Dys)Function

, 2013
Atherosclerosis is a chronic inflammatory disease involving the accumulation of monocytes and macrophages in the vascular wall. Monocytes and macrophages play a central role in the initiation and progression of atherosclerotic lesion development ...
Reto Asmis, Hong Kim, Sarah Ullevig
core   +1 more source

NADPH Oxidase 4 Mediates Monocyte Priming and Accelerated Chemotaxis Induced by Metabolic Stress

, 2012
Objective— Metabolic disorders increase monocyte chemoattractant protein-1 (MCP-1)-induced monocyte chemotaxis in mice. The goal of this study was to determine the molecular mechanisms responsible for the enhanced responsiveness ...
Debora Zamora, Reto Asmis, Qingwei Zhao, Sarah Ullevig, Hong Seok Kim, Chi Fung Lee   +5 more
core   +1 more source