Results 91 to 100 of about 6,885 (176)

Non‐triazine photosystem II inhibitors provide effective control of metabolic atrazine‐resistant Amaranthus tuberculatus

Pest Management Science, Volume 82, Issue 7, Page 6864-6876, July 2026.
Metabolism‐based atrazine‐resistant Amaranthus tuberculatus populations ACR and MCR exhibit little or no cross‐resistance to amicarbazone and metribuzin, suggesting that non‐halogenated Group 5 herbicides can be utilized to re‐establish effective control.
Alexander J Lopez, Ryan S Henry, Kip E Jacobs, Damilola A Raiyemo, Isabel S Werle, Patrick J Tranel   +5 more
wiley   +1 more source

Cellular redox imbalance and changes of protein S-glutathionylation patterns are associated with senescence induced by oncogenic H-ras.

PLoS ONE, 2012
H-Ras oncogene requires deregulation of additional oncogenes or inactivation of tumor suppressor proteins to increase cell proliferation rate and transform cells. In fact, the expression of the constitutively activated H-RasV12 induces cell growth arrest
Tatiana Armeni, Luisa Ercolani, Lorena Urbanelli, Alessandro Magini, Francesca Magherini, Armanda Pugnaloni, Francesco Piva, Alessandra Modesti, Carla Emiliani, Giovanni Principato   +9 more
doaj   +1 more source

Pharmacological treatment with a GABA(A) receptor modulator and a selective serotonin reuptake inhibitor as a mitigation strategy against aircraft noise‐induced cardiovascular and neuronal damage

British Journal of Pharmacology, Volume 183, Issue 13, Page 3762-3779, July 2026.
Abstract Background and Purpose Noise pollution, particularly by aircraft, is a significant risk factor for cardiovascular disease. Aircraft noise activates stress response pathways in the brain, via the amygdala, the sympathetic nervous system and the hypothalamic–pituitary–adrenal axis.
Ivana Kuntić, Marin Kuntić, Jiayin Zheng, Leonardo Nardi, Matthias Oelze, Arijan Valar, Dominika Mihaliková, Lea Strohm, Hans‐Georg Buchholz, Nicole Bausbacher, Simon Lange, Henning Ubbens, Qi Tang, Liyu Zhang, Guilherme Horta, Paul Stamm, Omar Hahad, Axel Methner, Sebastian Steven, Huige Li, Mathias Schreckenberger, Dilja Krueger‐Burg, Adrian Gericke, Michael J. Schmeisser, Thomas Münzel, Andreas Daiber   +25 more
wiley   +1 more source

Protein phosphatase PP2Cα S-glutathionylation regulates cell migration

Journal of Biological Chemistry
Redox signaling is a fundamental mechanism that controls all major biological processes partly via protein cysteine oxidations, including S-glutathionylation. Despite over 2000 cysteines identified to form S-glutathionylation in databases, the identification of redox cysteines functionally linked to a biological process of interest remains challenging.
Dhanushika S.K. Kukulage, Kusal T.G. Samarasinghe, Nadee N.J. Matarage Don, Madhu C. Shivamadhu, Kyosuke Shishikura, William Schiff, Faezeh Mashhadi Ramezani, Rayavarapu Padmavathi, Megan L. Matthews, Young-Hoon Ahn   +9 more
openaire   +2 more sources

Spontaneous Non‐Catalyzed Molecular Reactions and Interactions in the Human Body: Biomedical Implications

Advanced Science, Volume 13, Issue 36, 29 June 2026.
ABSTRACT The human body functions as a natural reactor for a vast network of chemical and biological reactions and physical interactions among small molecules, proteins, cells, and numerous other components. These reactions/interactions are essential for maintaining normal physiological functions.
Yuhao Cai, Chao Zhao
wiley   +1 more source

S-Glutathionylation of Cysteine 99 in the APE1 Protein Impairs Abasic Endonuclease Activity [PDF]

Journal of Molecular Biology, 2011
Human apurinic/apyrimidinic (AP) endonuclease 1 (APE1) is a central participant in the base excision repair pathway, exhibiting AP endonuclease activity that incises the DNA backbone 5' to an abasic site. Besides its prominent role as a DNA repair enzyme, APE1 was separately identified as a protein called redox effector factor 1, which is able to ...
Yun-Jeong, Kim, Daemyung, Kim, Jennifer L, Illuzzi, Sarah, Delaplane, Dian, Su, Michel, Bernier, Michael L, Gross, Millie M, Georgiadis, David M, Wilson   +8 more
openaire   +2 more sources

Attenuation of lung fibrosis in mice with a clinically relevant inhibitor of glutathione-S-transferase π [PDF]

, 2016
Idiopathic pulmonary fibrosis (IPF) is a debilitating lung disease characterized by excessive collagen production and fibrogenesis. Apoptosis in lung epithelial cells is critical in IPF pathogenesis, as heightened loss of these cells promotes fibroblast ...
Martina S. Iberg, Townsend, Danyelle M., Budd, Ralph C., Charles G. Irvin, Lahue, Karolyn G., Henderson, Colin J., Colin J. Henderson, Ralph C. Budd, Danyelle M. Townsend, Butnor, Kelly J., Kenneth D. Tew, Quan, Xi, Nolin, James D., van der Vliet, Albert, David H. McMillan, Anathy, Vikas, Stevenson Flemer, Iberg, Martina S., Albert van der Vliet, Yvonne M.W. Janssen-Heininger, van der Velden, Jos L. J., Tew, Kenneth D., McMillan, David H., James D. Nolin, Janssen-Heininger, Yvonne M. W., Taatjes, Douglas J., Douglas J. Taatjes, C. Roland Wolf, Robert W. Schneider, Sarah Abdalla, Abdalla, Sarah, Xi Qian, Schneider, Robert W., Irvin, Charles G., Casey, Dylan T., Dylan T. Casey, Vikas Anathy, Flemer, Stevenson, Jos L.J. van der Velden, Wolf, C. Roland, Karolyn G. Lahue, Kelly J. Butnor   +41 more
core   +1 more source

Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases

BMEMat, Volume 4, Issue 2, June 2026.
This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou, Jia Liu, Shulin Lai, Suhan Yin, Bingmin Luo, Longquan Shao, Yiyuan Kang   +6 more
wiley   +1 more source

Redox Regulation and Oxidative Stress in Health and Disease: Mechanisms and Therapeutic Targeting

MedComm – Future Medicine, Volume 5, Issue 2, June 2026.
Reactive species serve crucial roles which are tightly regulated in both physiological as well as disease states. At physiological levels, these species are integral to redox signaling, while uncontrolled redox promotes disease pathology. This review examines the dysregulation of these processes.
Mohammad Hossein Azadi, Azadeh Niknejad, Elaheh Amini   +2 more
wiley   +1 more source

A seleno-hormetine protects bone marrow hematopoietic cells against ionizing radiation-induced toxicities - Fig 1

, 2019
Reactive oxygen species (A and B), cell viability (C and D) protein S-glutathionylation (E and F) in the human liver cell lines HepG2 (A, C and E) and HepaRG (B, D and F). HepaRG or HepG2 cells were treated for 24 hours with 10 μM DSBA, PhSe)2 or Ebselen
Kenneth D. Tew (359414), Yanzhong Wang (51838), Daniela Giustarini (336169), Jie Zhang (64655), Ranieri Rossi (336167), Pierangelo Torquato (6645617), Desirée Bartolini (691630), Gavin Y. Wang (393428), Danyelle M. Townsend (359412), Francesco Galli (758374)   +9 more
core   +1 more source