Results 71 to 80 of about 6,885 (176)
Redox Biology, 2016 Nuclear Factor kappa B (NF-κB) is a transcription factor family critical in the activation of pro- inflammatory responses. The NF-κB pathway is regulated by oxidant-induced post-translational modifications. Protein S-glutathionylation, or the conjugation
Jane T. Jones +14 more
doaj +1 more source
Function and Regulation of Chloroplast Peroxiredoxin IIE
Antioxidants, 2021 Peroxiredoxins (PRX) are thiol peroxidases that are highly conserved throughout all biological kingdoms. Increasing evidence suggests that their high reactivity toward peroxides has a function not only in antioxidant defense but in particular in redox ...
Anna Dreyer +6 more
doaj +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend The genetic inactivation of one Mcu allele leads to sex‐specific changes in neuronal function in adult mice, that is, the firing of action potentials and the relationship between cytosolic and mitochondrial Ca2+ levels. The ability to produce NAD(P)H by stimulated neural tissue is largely preserved in male mice but delayed in ...
Jenna Gray +16 more
wiley +1 more source
Deciphering pro‐arrhythmogenic mechanisms of EPAC in human atrial cardiomyocytes
The Journal of Physiology, EarlyView.Abstract figure legend This study aimed to investigate the effect of exchange proteins directly activated by cAMP (EPAC) on the regulation of human atrial cardiomyocyte electrophysiology and their potential involvement in the onset of atrial fibrillation (AF).
Arthur Boileve +11 more
wiley +1 more source
Glutathione, glutathione disulfide, and S-glutathionylated proteins in cell cultures
Free Radical Biology and Medicine, 2015 The analysis of the global thiol-disulfide redox status in tissues and cells is a challenging task since thiols and disulfides can undergo artificial oxido-reductions during sample manipulation. Because of this, the measured values, in particular for disulfides, can have a significant bias. Whereas this methodological problem has already been addressed
GIUSTARINI, DANIELA +10 more
openaire +3 more sources
Effect of sodium nitrite on ischaemia and reperfusion-induced arrhythmias in anaesthetized dogs: is protein S-nitrosylation involved? [PDF]
PLoS ONE, 2015 To provide evidence for the protective role of inorganic nitrite against acute ischaemia and reperfusion-induced ventricular arrhythmias in a large animal model.Dogs, anaesthetized with chloralose and urethane, were administered intravenously with sodium
Mária Kovács +8 more
doaj +1 more source
Microbial Oxidative Stress in Food Fermentations: A Comprehensive Review
eFood, Volume 7, Issue 4, August 2026.Oxidative stress has a dual role in food fermentations: low ROS supports adaptive signaling, whereas excessive ROS causes cellular damage and process inhibition. Managing redox state as a controllable process variable can improve fermentation robustness and final food quality.
Wanrong Hu +11 more
wiley +1 more source
Redox Biology, 2021 Our lungs are exposed daily to airborne pollutants, particulate matter, pathogens as well as lung allergens and irritants. Exposure to these substances can lead to inflammatory responses and may induce endogenous oxidant production, which can cause ...
Cheryl van de Wetering +9 more
doaj +1 more source
Plant, Cell &Environment, Volume 49, Issue 8, Page 5421-5434, August 2026.ABSTRACT Glutathione, including reduced glutathione (GSH) and oxidized glutathione (GSSG), is the major non‐protein thiol‐based redox buffer. There are diurnal rhythms in total glutathione level and in this work, we investigate whether these oscillations might be indicative of circadian regulation of total glutathione homeostasis.
Desiré Cano‐Yelo +5 more
wiley +1 more source
Effect of GSTP ablation on protein S-glutathionylation responses to ROS or RNS.
, 2014 (A) Crude BMCs and (B) BMDDCs derived from WT or Gstp1/p2−/− mice were exposed to various concentrations of H2O2 (1, 5 or 10 mM) (left panel) or PABA/NO (0.5, 1 or 2 µM) (right panel), at 37°C for 15 min.
Elizabeth E. Jones (628973) +10 more
core +1 more source