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Protein S-acylation: Pathological mechanisms and novel therapeutic targets for diabetic complications. [PDF]

open access: yesChin Herb Med
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Protein S mRNA in Patients with Protein S Deficiency

Thrombosis and Haemostasis, 1995
SummaryA protein S gene polymorphism, detectable by restriction analysis (BstXI) of amplified exonic sequences (exon 15), was studied in seven Italian families with protein S deficiency. In the 17 individuals heterozygous for the polymorphism the study was extended to platelet mRNA through reverse transcription, amplification and densitometric analysis.
SACCHI E   +6 more
openaire   +2 more sources

Protein S

2013
Protein S (PS) is a vitamin K-dependent plasma glycoprotein. Around 60-70% of PS in plasma is noncovalently bound to C4-binding protein (C4BP). Free PS functions as a cofactor that enhances the activity of activated protein C (APC) in the proteolytic degradation of activated factors V and VIII.
Mirta, Hepner, Vasiliki, Karlaftis
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Protein S Deficiency

Thrombosis and Haemostasis, 1997
The protein C (PC) pathway, with its cofactor protein S (PS), is an important natural antithrombotic mechanism. Patients with phenotypic PS deficiency may develop recurrent thrombosis during adulthood, with a probability of remaining free of thrombosis of about 50% at age 45.
D, Borgel, S, Gandrille, M, Aiach
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