Results 261 to 270 of about 28,039,605 (307)

Analytical Considerations for Free Protein S Assays in Protein S Deficiency

Thrombosis and Haemostasis, 2001
SummaryProtein S is an anticoagulant protein that circulates in plasma in complex with C4b-binding protein (C4BP) or in free form. Deficiency of protein S increases the risk of venous thrombosis. Measurement of free protein S, as compared to total levels, has been shown to be superior for prediction of protein S deficiency.
K E, Persson, A, Hillarp, B, Dahlbäck
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PROTEIN S DEFICIENCY AND ANTIBODIES TO PROTEIN S IN PATIENTS WITH BEHCET'S DISEASE

Thrombosis Research, 1997
Thrombosis occurs in 20 to 30% of patients with Behçet's disease (BD). Most of the reported hemostatic abnormalities are related to the inflammatory syndrome. We have assessed the activity of antithrombin III, protein C and protein S (PS), in 30 patients with BD and in 30 healthy controls. Thrombosis antecedents were found in 16 patients.
S, Guermazi, M, Hamza, K, Dellagi
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DSC study of the thermal stability of S-protein and S-peptide/S-protein.

Biochemistry, 1996
The thermal denaturation of S-protein is investigated at pH 7.0 by means of DSC measurements. The process is reversible and can be assimilated to a two-state transition. The low values of denaturation temperature and enthalpy, between 38.5 and 40.0 °C and 165 and 180 kJ mol-1, respectively, demonstrate that the loss of S-peptide strongly decreases the ...
G. GRAZIANO, F. CATANZANO, GIANCOLA, CONCETTA, G. BARONE   +3 more
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Protein S deficiency: a clinical perspective

Haemophilia, 2008
Summary.  Protein S (PS) is an extensively studied protein with an important function in the down‐regulation of thrombin generation. Because of the presence of a pseudogene and two different forms of PS in plasma, a bound and a free form, it is one of the most difficult thrombophilias to study.
Ten Kate, M. K., Van der Meer, J.
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Reassembly of S-layer proteins

Nanotechnology, 2014
Crystalline bacterial cell surface layers (S-layers) represent the outermost cell envelope component in a broad range of bacteria and archaea. They are monomolecular arrays composed of a single protein or glycoprotein species and represent the simplest biological membranes developed during evolution.
Dietmar, Pum, Uwe B, Sleytr
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S-Adenosylmethionine and protein methylation

Amino Acids, 2005
The enzymes responsible for protein methylation by S-adenosylmethionine, both at the carboxyl groups and at the nitrogen groups, are reviewed. The possibility that the reactions involved may be reversible is also considered.
GRILLO M. A., COLOMBATTO, Sebastiano
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Regulation of coagulation by protein S

Current Opinion in Hematology, 2008
Protein S has been one of the least mechanistically understood amongst the vitamin K-dependent coagulation proteins, and diagnosis of protein S deficiency and quantification of the associated thrombotic risk are not straightforward. In this review, the regulation of thrombin generation by protein S and the pathophysiological implications of protein S ...
Elisabetta, Castoldi, Tilman M, Hackeng
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The Role of S—S Groups in Proteins

1974
The disulfide group is the most widespread of the covalent bonds in proteins that can link different parts of a polypeptide chain or different chains, and can thus play a part in maintaining the secondary, tertiary, and quaternary structures of proteins.
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S-Thiolation of Protein Sulfhydryls

1991
Many cellular proteins have highly reactive sulfhydryls that are especially prone to modification during oxidative stress. Proteins with at least one “reactive” sulfhydryl are prevelant in cytoplasm, membranes, and nuclei, and the concentration of these reactive sites is impressive, reaching or exceeding the concentration of glutathione in many cells ...
J A, Thomas, E M, Park, Y C, Chai, R, Brooks, K, Rokutan, R B, Johnston   +5 more
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Protein S and the Nephrotic Syndrome

Annals of Internal Medicine, 1988
Excerpt To the editor: Vigano-D'Angelo and associates (1) present interesting hypotheses on protein S in nephrotic syndrome, but I do not believe their data support their conclusions.
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