Results 61 to 70 of about 28,039,605 (307)

THROMBOPHILIA PROFILE IN YOUNG PATIENTS OF CEREBROVASCULAR ACCIDENT- AN INSTITUTION BASED STUDY

Pakistan Armed Forces Medical Journal, 2018
Objective: To find out frequency of different causes of thrombophilia in young patients of cerebrovascular accidents. Study Design: Cross sectional descriptive study.
Amna Khalid, Saleem Ahmed Khan, Nasir udin, Wasim Alamgir, Rabia Anwar, Rabia Anwar   +5 more
doaj  

Natural anticoagulant protein levels in patients with transfusion-dependent thalassemia in Nineveh province

Iraqi Journal of Hematology
BACKGROUND: Protein C (PC), protein S (PS), and antithrombin levels dramatically reduced in thalassemic patients, particularly those with splenectomies and few transfusions, indicating a significant involvement in hypercoagulability.
Samar Saleh Saadi
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Signaling beyond Punching Holes: Modulation of Cellular Responses by Vibrio cholerae Cytolysin

Toxins, 2015
Pore-forming toxins (PFTs) are a distinct class of membrane-damaging cytolytic proteins that contribute significantly towards the virulence processes employed by various pathogenic bacteria.
Barkha Khilwani, Kausik Chattopadhyay
doaj   +1 more source

Amelioration of Diabetes by Protein S [PDF]

Diabetes, 2016
Protein S is an anticoagulant factor that also regulates inflammation and cell apoptosis. The effect of protein S on diabetes and its complications is unknown. This study compared the development of diabetes between wild-type and transgenic mice overexpressing human protein S and the development of diabetic glomerulosclerosis between mice treated with ...
Taro, Yasuma, Yutaka, Yano, Corina N, D'Alessandro-Gabazza, Masaaki, Toda, Paloma, Gil-Bernabe, Tetsu, Kobayashi, Kota, Nishihama, Josephine A, Hinneh, Rumi, Mifuji-Moroka, Ziaurahman, Roeen, John, Morser, Isaac, Cann, Iwasa, Motoh, Yoshiyuki, Takei, Esteban C, Gabazza   +14 more
openaire   +2 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Dietary soy galactooligosaccharides affect the performance, intestinal function, and gut microbiota composition of growing chicks

Poultry Science, 2023
: The objective of this experiment was to investigate the effects of the dietary soy galactooligosaccharides (GOS), raffinose and stachyose, on performance, gastrointestinal health, and systemic stress in young broilers.
K.D. Teague, G. Tellez-Isaias, Jianmin Chai, V. Petrone-Garcia, C.N. Vuong, A. Blanch, S.H. Rasmussen, K. Brown, Jiangchao Zhao, S.J. Rochell   +9 more
doaj   +1 more source

Towards characterization of DNA structure under physiological conditions in vivo at the single-molecule level using single-pair FRET [PDF]

, 2012
Fluorescence resonance energy transfer (FRET) under in vivo conditions is a well-established technique for the evaluation of populations of protein bound/unbound nucleic acid (NA) molecules or NA hybridization kinetics. However, in vivo FRET has not been
Polıvka, T., Adamec, F., Sub Cellular Protein Chemistry, Fessl, T., Foldynová-Trantírková, S., Trantirek, L., Cellular Protein Chemistry, Vácha, F.   +7 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Immunological Study of Aborted Women Infected with Toxoplasmosis in Basrah Province

Journal of Medical Sciences
Background Toxoplasmosis is regarded as one of the chief sources of miscarriage in pregnant women which caused by an apicomplexan obligatory intracellular parasites called Toxoplasma gondii.
Baydaa F. Swadi, Dawood Mahdi, Khalid Mezeal   +2 more
doaj   +1 more source