Results 71 to 80 of about 2,642,890 (372)

MASSP3: A System for Predicting Protein Secondary Structure

EURASIP Journal on Advances in Signal Processing, 2006
A system that resorts to multiple experts for dealing with the problem of predicting secondary structures is described, whose performances are comparable to those obtained by other state-of-the-art predictors.
Armano Giuliano, Orro Alessandro, Vargiu Eloisa   +2 more
doaj   +1 more source

3-State Protein Secondary Structure Prediction based on SCOPe Classes

Brazilian Archives of Biology and Technology, 2021
Improving the accuracy of protein secondary structure prediction has been an important task in bioinformatics since it is not only the starting point in obtaining tertiary structure in hierarchical modeling but also enhances sequence analysis and ...
Sema Atasever, Nuh Azgınoglu, Hasan Erbay, Zafer Aydın   +3 more
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

NMR analysis of synthetic human serum albumin alpha-helix 28 identifies structural distortion upon amadori modification [PDF]

, 2005
The non-enzymatic reaction between reducing sugars and long-lived proteins in vivo results in the formation of glycation and advanced glycation end products, which alter the properties of proteins including charge, helicity, and their tendency to ...
Howard, Mark J., Smales, Christopher Mark   +1 more
core   +1 more source

DSC: public domain protein secondary structure prediction [PDF]

Bioinformatics, 1997
1. DSC has high accuracy. It has a prediction accuracy of 70.1% (per residue) on a standard set of 126 proteins. This percentage was confirmed by the recent CASP2 blind prediction challenge (see below). 2. DSC is based on simple linear statistics. Existing highaccuracy prediction methods are 'black-box' predictors based on complex non-linear statistics
King, Ross D., Saqi, Mansoor, Sayle, Roger, Stern Berg, Michael J E   +3 more
openaire   +3 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

A model for the force stretching double-stranded chain molecules

, 2002
We modify and extend the recently developed statistical mechanical model for predicting the thermodynamic properties of chain molecules having noncovalent double-stranded conformations, as in RNA or ssDNA, and $\beta-$sheets in protein, by including the ...
Fei Liu, Luru Dai, Müller M., Rief M., Zhong-can Ou-Yang, Zhou H.-J.   +5 more
core   +1 more source

Properties and origins of protein secondary structure [PDF]

Physical Review E, 1994
12 pages (+4 figures, included in a single postscript file), LaTeX + RevTeX 3 ...
Socci, Nicholas D., Bialek, William S., Onuchic, Jose' Nelson   +2 more
openaire   +3 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Improved Chou-Fasman method for protein secondary structure prediction

BMC Bioinformatics, 2006
Background Protein secondary structure prediction is a fundamental and important component in the analytical study of protein structure and functions. The prediction technique has been developed for several decades.
Huang Zhengge, Gu Fei, Chen Hang
doaj   +1 more source