Results 61 to 70 of about 1,631,834 (287)

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul, Jatuporn Sujjitjoon, Pa‐thai Yenchitsomanus, Kridtin Jarutatsanangkoon, Ng Wei Loon, Kleebsabai Sanpakit, Jassada Buaboonnam, Chayamon Takpradit, Pornpimon Yuti, Nunghathai Sawasdee, Piriya Luangwattananun, Siripakorn Sangkitporn, Arnan Limmahachai, La‐ongsri Atchaneeyasakul   +13 more
wiley   +1 more source

TMPSS: A Deep Learning-Based Predictor for Secondary Structure and Topology Structure Prediction of Alpha-Helical Transmembrane Proteins

Frontiers in Bioengineering and Biotechnology, 2021
Alpha transmembrane proteins (αTMPs) profoundly affect many critical biological processes and are major drug targets due to their pivotal protein functions.
Zhe Liu, Zhe Liu, Yingli Gong, Yihang Bao, Yuanzhao Guo, Han Wang, Guan Ning Lin, Guan Ning Lin   +7 more
doaj   +1 more source

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel, Patricia Pastura, Joshua P. Scallan, Timothy D. Le Cras   +3 more
wiley   +1 more source

MASSP3: A System for Predicting Protein Secondary Structure

EURASIP Journal on Advances in Signal Processing, 2006
A system that resorts to multiple experts for dealing with the problem of predicting secondary structures is described, whose performances are comparable to those obtained by other state-of-the-art predictors.
Armano Giuliano, Orro Alessandro, Vargiu Eloisa   +2 more
doaj   +1 more source

Fourier Analysis of Conservation Patterns in Protein Secondary Structure

Computational and Structural Biotechnology Journal, 2017
Residue conservation is a common observation in alignments of protein families, underscoring positions important in protein structure and function. Though many methods measure the level of conservation of particular residue positions, currently we do not
Ashok Palaniappan, Eric Jakobsson
doaj   +1 more source

Functional Properties of Protein Hydrolyzate from Ribbon Fish (Lepturacanthus Savala) as Prepared by Enzymatic hydrolysis

International Journal of Food Properties, 2022
Fish protein hydrolyzates (FPH) are breakdown products of hydrolysis and are gaining importance in the field of nutraceuticals and functional foods due to their bioactive properties, high nutritional value, solubility, and digestibility. This study aimed
Undiganalu Gangadharappa Yathisha, Sneha Vaidya, Mamatha Bangera Sheshappa   +2 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

DSC: public domain protein secondary structure prediction [PDF]

Bioinformatics, 1997
1. DSC has high accuracy. It has a prediction accuracy of 70.1% (per residue) on a standard set of 126 proteins. This percentage was confirmed by the recent CASP2 blind prediction challenge (see below). 2. DSC is based on simple linear statistics. Existing highaccuracy prediction methods are 'black-box' predictors based on complex non-linear statistics
King, Ross D., Saqi, Mansoor, Sayle, Roger, Stern Berg, Michael J E   +3 more
openaire   +3 more sources

Improved Chou-Fasman method for protein secondary structure prediction

BMC Bioinformatics, 2006
Background Protein secondary structure prediction is a fundamental and important component in the analytical study of protein structure and functions. The prediction technique has been developed for several decades.
Huang Zhengge, Gu Fei, Chen Hang
doaj   +1 more source

Properties and origins of protein secondary structure [PDF]

Physical Review E, 1994
12 pages (+4 figures, included in a single postscript file), LaTeX + RevTeX 3 ...
Socci, Nicholas D., Bialek, William S., Onuchic, Jose' Nelson   +2 more
openaire   +3 more sources