A Computational Model of the LGI1 Protein Suggests a Common Binding Site for ADAM Proteins [PDF]
, 2011 Mutations of human leucine-rich glioma inactivated (LGI1) gene encoding the epitempin protein cause autosomal dominant temporal lateral epilepsy (ADTLE), a rare familial partial epileptic syndrome.
Leonardi, Emanuela +23 more
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Improved Chou-Fasman method for protein secondary structure prediction
BMC Bioinformatics, 2006 Background Protein secondary structure prediction is a fundamental and important component in the analytical study of protein structure and functions. The prediction technique has been developed for several decades.
Huang Zhengge, Gu Fei, Chen Hang
doaj +1 more source
Improved probability graph model for protein secondary structure prediction
Journal of Hebei University of Science and Technology, 2016 Protein secondary structure is closely related to protein tertiary structure and function, and became a hot topic in bioinformatics. The probability graph model HMM (Hidden Markov model) is an important tool in this field.
Lingqi ZHAO +4 more
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A physical basis for protein secondary structure [PDF]
Proceedings of the National Academy of Sciences, 1999 A physical theory of protein secondary structure is proposed and tested by performing exceedingly simple Monte Carlo simulations. In essence, secondary structure propensities are predominantly a consequence of two competing local effects, one favoring hydrogen bond formation in helices and turns, the other opposing the attendant reduction in sidechain ...
R, Srinivasan, G D, Rose
openaire +2 more sources
Protein secondary structure prediction by artificial neural networks [PDF]
, 2010 碩士蛋白質的組成控制著它的功能，而人體裡面有數百甚至數千個蛋白質的存在，因此我們會想要去知道蛋白質個別的功用及它們之間彼此是如何互動的，而這個領域被稱作蛋白質體學，它的目的主要是在調查在生物裡面的蛋白質的功能為何。 蛋白質的功能是決定於它的架構，目前X光結晶繞射照影(X-ray Crystallography) 與核磁共振(Nuclear Magnetic Resonance)(NMR)都能夠視覺化蛋白質的三維架構。然而它們是耗費時間且昂貴的，而所耗費的時間長達數週到數個月，另外也有解析上的問題 ...
張建蒼; Chang, Jian-tsang
core
Improving classification in protein structure databases using text mining [PDF]
, 2009 Background: The classification of protein domains in the CATH resource is primarily based on structural comparisons, sequence similarity and manual analysis.
Jones, DT +11 more
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Structural characterisation of pre-processed thermoplastic protein derived from bloodmeal [PDF]
, 2012 Additives are required to convert bloodmeal powder into an extrudable thermoplastic protein-based bioplastic. These include a protein denaturant, a surfactant, a reducing agent and plasticisers.
Verbeek, Casparus Johan R. +2 more
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Using neural networks and evolutionary information in decoy discrimination for protein tertiary structure prediction [PDF]
, 2008 Background: We present a novel method of protein fold decoy discrimination using machine learning, more specifically using neural networks. Here, decoy discrimination is represented as a machine learning problem, where neural networks are used to learn ...
Jones, DT +3 more
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Protein-RNA interactions: a structural analysis [PDF]
, 2001 A detailed computational analysis of 32 protein-RNA complexes is presented. A number of physical and chemical properties of the intermolecular interfaces are calculated and compared with those observed in protein-double-stranded DNA and protein-single ...
Daley, DT +9 more
core
The crystal structure of the globular domain of sheep prion protein [PDF]
, 2004 The prion protein PrP is a naturally occurring polypeptide that becomes transformed from a normal conformation to that of an aggregated form, characteristic of pathological states in fatal transmissible spongiform conditions such as Creutzfeld–Jacob ...
Vasisht N +28 more
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