Combining protein evolution and secondary structure [PDF]
An evolutionary model that combines protein secondary structure and amino acid replacement is introduced. It allows likelihood analysis of aligned protein sequences and does not require the underlying secondary (or tertiary) structures of these sequences to be known.
J L, Thorne, N, Goldman, D T, Jones
openaire +2 more sources
Prediction of Protein Function Using Statistically Significant Sub-Structure Discovery [PDF]
Proteins perform a vast number of functional roles. The number of protein structures available for analysis continues to grow and, with the development of methods to predict protein structure directly from genetic sequence without imaging technology, the
Lucas, Craig
core
CATHEDRAL: A fast and effective algorithm to predict folds and domain boundaries from multidomain protein structures [PDF]
We present CATHEDRAL, an iterative protocol for determining the location of previously observed protein folds in novel multidomain protein structures. CATHEDRAL builds on the features of a fast secondary-structure-based method ( using graph theory) to ...
Oliver C Redfern +22 more
core +1 more source
A dengue outbreak abruptly occurred at the border of China, Myanmar, and Laos in June 2017. By November 3rd 2017, 1184 infected individuals were confirmed as NS1-positivein Xishuangbanna, a city located at the border.
Songjiao Wen +28 more
doaj +1 more source
Universality in protein residue networks [PDF]
Residue networks representing 595 nonhomologous proteins are studied. These networks exhibit universal topological characteristics as they belong to the topological class of modular networks formed by several highly interconnected clusters separated by ...
Estrada, Ernesto +3 more
core +1 more source
Protein structure prediction [Elektronisk resurs] : Zinc-binding sites, one-dimensional structure and remote homology [PDF]
Predicting the three-dimensional (3D) structure of proteins is a central problem in biology. These computationally predicted 3D protein structures have been successfully applied in many fields of biomedicine, e.g.
Hovmöller, Sven, +3 more
core
Why similar protein sequences encode similar three-dimensional structures? [PDF]
Evolutionarily related proteins have similar sequences. Such similarity is called homology and can be described using substitution matrices such as Blosum 60.
Zielenkiewicz, Piotr +1 more
core
Physicochemical Characteristics of Protein Isolated from Thraustochytrid Oilcake
The oil from thraustochytrids, unicellular heterotrophic marine protists, is increasingly used in the food and biotechnological industries as it is rich in omega-3 fatty acids, squalene and a broad spectrum of carotenoids.
Thi Linh Nham Tran +3 more
doaj +1 more source
Inherent structural disorder and dimerisation of murine norovirus NS1-2 protein [PDF]
Human noroviruses are highly infectious viruses that cause the majority of acute, non-bacterial epidemic gastroenteritis cases worldwide. The first open reading frame of the norovirus RNA genome encodes for a polyprotein that is cleaved by the viral ...
Krause Kurt L. +17 more
core +1 more source
A computer system to perform structure comparison using TOPS representations of protein structure [PDF]
We describe the design and implementation of a fast topology–based method for protein structure comparison. The approach uses the TOPS topological representation of protein structure, aligning two structures using a common discovered pattern and ...
Viksna, J +3 more
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