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Deep learning for protein secondary structure prediction: Pre and post-AlphaFold. [PDF]

open access: yesComput Struct Biotechnol J, 2022
This paper aims to provide a comprehensive review of the trends and challenges of deep neural networks for protein secondary structure prediction (PSSP). In recent years, deep neural networks have become the primary method for protein secondary structure
Ismi DP, Pulungan R, Afiahayati.
europepmc   +2 more sources

Discovering the Ultimate Limits of Protein Secondary Structure Prediction. [PDF]

open access: yesBiomolecules, 2021
Secondary structure prediction (SSP) of proteins is an important structural biology technique with many applications. There have been ~300 algorithms published in the past seven decades with fierce competition in accuracy.
Ho CT, Huang YW, Chen TR, Lo CH, Lo WC.
europepmc   +2 more sources

Protein secondary structure: Entropy, correlations and prediction [PDF]

open access: yesBioinformatics, 2003
Is protein secondary structure primarily determined by local interactions between residues closely spaced along the amino acid backbone, or by non-local tertiary interactions?
Brenner, Steven E., Crooks, Gavin E.
core   +9 more sources

Multistage Combination Classifier Augmented Model for Protein Secondary Structure Prediction. [PDF]

open access: yesFront Genet, 2022
In the field of bioinformatics, understanding protein secondary structure is very important for exploring diseases and finding new treatments. Considering that the physical experiment-based protein secondary structure prediction methods are time ...
Zhang X   +6 more
europepmc   +2 more sources

Ensemble deep learning models for protein secondary structure prediction using bidirectional temporal convolution and bidirectional long short-term memory. [PDF]

open access: yesFront Bioeng Biotechnol, 2023
Protein secondary structure prediction (PSSP) is a challenging task in computational biology. However, existing models with deep architectures are not sufficient and comprehensive for deep long-range feature extraction of long sequences.
Yuan L, Ma Y, Liu Y.
europepmc   +2 more sources

Deep Ensemble Learning with Atrous Spatial Pyramid Networks for Protein Secondary Structure Prediction. [PDF]

open access: yesBiomolecules, 2022
The secondary structure of proteins is significant for studying the three-dimensional structure and functions of proteins. Several models from image understanding and natural language modeling have been successfully adapted in the protein sequence study ...
Guo Y, Wu J, Ma H, Wang S, Huang J.
europepmc   +2 more sources

Protein Secondary Structure Prediction With a Reductive Deep Learning Method. [PDF]

open access: yesFront Bioeng Biotechnol, 2021
Protein secondary structures have been identified as the links in the physical processes of primary sequences, typically random coils, folding into functional tertiary structures that enable proteins to involve a variety of biological events in life ...
Lyu Z, Wang Z, Luo F, Shuai J, Huang Y.
europepmc   +2 more sources

Impact of Multi-Factor Features on Protein Secondary Structure Prediction. [PDF]

open access: yesBiomolecules
Protein secondary structure prediction (PSSP) plays a crucial role in resolving protein functions and properties. Significant progress has been made in this field in recent years, and the use of a variety of protein-related features, including amino acid
Dong B   +5 more
europepmc   +2 more sources

A dynamic Bayesian network approach to protein secondary structure prediction [PDF]

open access: yesBMC Bioinformatics, 2008
Background Protein secondary structure prediction method based on probabilistic models such as hidden Markov model (HMM) appeals to many because it provides meaningful information relevant to sequence-structure relationship.
Zhu Huaiqiu, Yao Xin-Qiu, She Zhen-Su
doaj   +5 more sources

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