Results 41 to 50 of about 415,112 (277)

PROTINFO: secondary and tertiary protein structure prediction [PDF]

open access: yesNucleic Acids Research, 2003
Information about the secondary and tertiary structure of a protein sequence can greatly assist biologists in the generation and testing of hypotheses, as well as design of experiments. The PROTINFO server enables users to submit a protein sequence and request a prediction of the three-dimensional (tertiary) structure based on comparative modeling ...
Ling-Hong, Hung, Ram, Samudrala
openaire   +2 more sources

Improving prediction of secondary structure, local backbone angles, and solvent accessible surface area of proteins by iterative deep learning [PDF]

open access: yes, 2015
Direct prediction of protein structure from sequence is a challenging problem. An effective approach is to break it up into independent sub-problems. These sub-problems such as prediction of protein secondary structure can then be solved independently ...
Dehzangi, A.   +8 more
core   +1 more source

Protein Secondary Structure Prediction Using Dynamic Programming [PDF]

open access: yesActa Biochimica et Biophysica Sinica, 2005
In the present paper, we describe how a directed graph was constructed and then searched for the optimum path using a dynamic programming approach, based on the secondary structure propensity of the protein short sequence derived from a training data set. The protein secondary structure was thus predicted in this way.
Jing, Zhao   +3 more
openaire   +2 more sources

An evolutionary method for learning HMM structure: prediction of protein secondary structure

open access: yesBMC Bioinformatics, 2007
Background The prediction of the secondary structure of proteins is one of the most studied problems in bioinformatics. Despite their success in many problems of biological sequence analysis, Hidden Markov Models (HMMs) have not been used much for this ...
Won Kyoung-Jae   +3 more
doaj   +1 more source

Protein Secondary Structure Prediction

open access: yes, 2008
{"references": ["Cuff, J. A. and Barton, G.J. \"Evaluation and improvement of multiple\nsequence methods for protein secondary structure prediction. Proteins,\n34, 1999, pp. 508-519.", "Cuff, J.A. and Barton G.J. \"Application of multiple sequence alignment\nprofiles to improve protein secondary structure prediction\" Proteins, 40,\n2000, pp. 502-511.",
Manpreet Singh   +2 more
openaire   +1 more source

The Carboxyl-Terminal Segment of Apolipoprotein A-V Undergoes a Lipid-Induced Conformational Change [PDF]

open access: yes, 2010
Apolipoprotein (apo) A-V is a 343-residue, multidomain protein that plays an important role in regulation of plasma triglyceride homeostasis. Primary sequence analysis revealed a unique tetraproline sequence (Pro293-Pro296) near the carboxyl terminus of ...
Lee, B. L.   +4 more
core   +2 more sources

Structure prediction for the helical skeletons detected from the low resolution protein density map [PDF]

open access: yes, 2010
Background The current advances in electron cryo-microscopy technique have made it possible to obtain protein density maps at about 6-10 Å resolution. Although it is hard to derive the protein chain directly from such a low resolution map, the location ...
Jing He, Kamal Al Nasr, Weitao Sun
core   +3 more sources

Improved Chou-Fasman method for protein secondary structure prediction

open access: yesBMC Bioinformatics, 2006
Background Protein secondary structure prediction is a fundamental and important component in the analytical study of protein structure and functions. The prediction technique has been developed for several decades.
Huang Zhengge, Gu Fei, Chen Hang
doaj   +1 more source

A Simple Comparison between Specific Protein Secondary Structure Prediction Tools

open access: yesTropical Agricultural Research, 2012
A comparative evaluation of five widely used protein secondary structure prediction programs available in World Wide Web was carried out. Secondary structure data of ten proteins containing 190 secondary structure motifs were collected from Protein Data ...
TJ Koswatta   +2 more
doaj   +1 more source

MUST-CNN: A Multilayer Shift-and-Stitch Deep Convolutional Architecture for Sequence-based Protein Structure Prediction

open access: yes, 2016
Predicting protein properties such as solvent accessibility and secondary structure from its primary amino acid sequence is an important task in bioinformatics.
Lanchantin, Jack   +2 more
core   +1 more source

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