Results 51 to 60 of about 415,112 (277)

Evaluation of in silico protein secondary structure prediction methods by employing statistical techniques

Biomedical and Biotechnology Research Journal, 2017
Background: With the advent of many new advanced techniques, sequences of a number of proteins have been made available. But the relative paucity of the experimentally determined three-dimensional structures of these proteins has paved way for the ...
Kandavelmani Angamuthu, Shanmughavel Piramanayagam   +1 more
doaj   +1 more source

Empirical study of deep neural network architectures for protein secondary structure prediction [PDF]

Protein secondary structure prediction is a sub-problem of protein structure prediction. Instead of fully recovering the whole three dimensional structure from amino acid sequence, protein secondary structure prediction only aimed at predicting the local
Du, Ming
core   +1 more source

Improved prediction of RNA secondary structure by integrating the free energy model with restraints derived from experimental probing data. [PDF]

, 2016
PublishedEvaluation StudiesJournal ArticleResearch Support, Non-U.S. Gov'tRecently, several experimental techniques have emerged for probing RNA structures based on high-throughput sequencing.
Ding, X, Hu, X, Liu, T, Lu, ZJ, Mathews, DH, Shi, B, Wu, Y, Yang, ZR, Yip, KY   +8 more
core   +1 more source

Aligning Protein Sequences with Predicted Secondary Structure [PDF]

Journal of Computational Biology, 2010
Accurately aligning distant protein sequences is notoriously difficult. Since the amino acid sequence alone often does not provide enough information to obtain accurate alignments under the standard alignment scoring functions, a recent approach to improving alignment accuracy is to use additional information such as secondary structure.
John, Kececioglu, Eagu, Kim, Travis, Wheeler   +2 more
openaire   +2 more sources

Recoverable One-dimensional Encoding of Three-dimensional Protein Structures

, 2005
Protein one-dimensional (1D) structures such as secondary structure and contact number provide intuitive pictures to understand how the native three-dimensional (3D) structure of a protein is encoded in the amino acid sequence.
A. R. Kinjo, Berman, Havel, K. Nishikawa, Kabsch, Kinjo, Nakai, Plaxco, Porto, Vendruscolo, Wang   +10 more
core   +2 more sources

Abundance of intrinsic disorder in SV-IV, a multifunctional androgen-dependent protein secreted from rat seminal vesicle [PDF]

, 2007
The potent immunomodulatory, anti-inflammatory and procoagulant properties of the protein no. 4 secreted from the rat seminal vesicle epithelium (SV-IV) have been previously found to be modulated by a supramolecular monomer-trimer ...
Ambrosone, Bairoch, Bornberg-Bauer, Bourhis, Cai, Caporale, Cheng, Coeytaux, Csizmók, Doszatányi, Dosztányi, Dunker, Dunker, Dyson, D’Ambrosio, Esposito, Ferron, Gaboriaud, Galzitskaya, Galzitskaya, Galzitskaya, Garbuzynskiy, Harris, Hirose, Ialenti, Kandala, Kyte, Li, Lin, Linding, Linding, Liu, Lupas, MacCallum, McDonald, Metafora, Metafora, Miele, Murzin, Obradovic, Obradovic, Ostrowski, Pan, Prilusky, Quevillon-Cheruel, Radivojac, Ragone, Romero, Romero, Rüping, Shimizu, Shimizu, Sickmeier, Stiuso, Stiuso, Tompa, Tufano, Uversky, Uversky, Vucetic, Ward, Weathers, Weathers, Wolf, Wootton, Wright, Yang   +66 more
core   +3 more sources

Protein secondary structure: category assignment and predictability [PDF]

FEBS Letters, 2001
In the last decade, the prediction of protein secondary structure has been optimized using essentially one and the same assignment scheme known as DSSP. We present here a different scheme, which is more predictable. This scheme predicts directly the hydrogen bonds, which stabilize the secondary structures.
Andersen, Claus A, Bohr, Henrik, Brunak, Søren   +2 more
openaire   +2 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Alignment of helical membrane protein sequences using AlignMe [PDF]

, 2013
Few sequence alignment methods have been designed specifically for integral membrane proteins, even though these important proteins have distinct evolutionary and structural properties that might affect their alignments.
Forrest, Lucy R., Khafizov, Kamil, Stamm, Marcus, Staritzbichler, René   +3 more
core   +3 more sources

Prediction of Protein Secondary Structure

Jurnal Teknologi, 2012
Dengan wujudnya projek jujukan DNA secara besar–besaran, teknik yang tepat untuk meramalkan struktur protein diperlukan. Masalah meramalkan struktur protein daripada jujukan DNA pada dasarnya masih belum dapat diselesaikan walaupun kajian intensif telah dilakukan selama lebih daripada tiga dekad. Dalam kertas kerja ini, teori asas struktur protein
Satya Nanda Vel Arjunan, Safaai Deris, Rosli Md Illias   +2 more
openaire   +1 more source