Results 101 to 110 of about 5,630,720 (303)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Pathogen-induced protein secretion in plants.
, 2008 The sugar alcohol mannitol is an important carbohydrate in many plants and fungi that has well-documented roles in both metabolism and osmoprotection. In addition, mannitol is an antioxidant, and as such might play a role in host-pathogen interactions ...
Cheng, Fang-yi
core
Protein translocation across mitochondrial membranes [PDF]
, 1992 Protein translocation across biological membranes is of fundamental importance for the biogenesis of organelles and in protein secretion. We will give an overview of the recent achievements in the understanding of protein translocation across ...
Walter Neupert +3 more
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
The ArfGEF GBF-1 Is Required for ER Structure, Secretion and Endocytic Transport in C. elegans [PDF]
, 2013 Small GTPases of the Sar/Arf family are essential to generate transport containers that mediate communication between organelles of the secretory pathway.
Anne Spang +21 more
core +2 more sources
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
Frontiers in Microbiology, 2019 Protein secretion from the cell cytoplasm to the outside is essential for life. Bacteria do so for a range of membrane associated and extracellular activities, including envelope biogenesis, surface adherence, pathogenicity, and degradation of noxious ...
Ian Collinson
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
mBioMycoplasma pneumoniae (Mp) causes both pulmonary and extrapulmonary infections in humans, and its virulence is largely attributed to the community-acquired respiratory distress syndrome (CARDS) toxin. CARDS toxin is transiently expressed during Mp growth
K. Sreenath +5 more
doaj +1 more source
Frontiers in Plant Science, 2015 The steadily increasing number of sequenced fungal and oomycete genomes has enabled detailed studies of how these eukaryotic microbes infect plants and cause devastating losses in food crops.
Jana eSperschneider +7 more
doaj +1 more source