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Basic Protein Sequence Analysis
Current Protocols in Molecular Biology, 2005AbstractPrediction of molecular function of proteins has become an important task in the genomics era. A wide variety of sequence analysis tools are available to biologists for this task. We have selected one or two primary protocols for tasks such as domain detection, subcellular localization, and motif detection.
Nandini, Krishnamurthy +1 more
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Analysis of protein sequence similarity
2010 IEEE Fifth International Conference on Bio-Inspired Computing: Theories and Applications (BIC-TA), 2010This paper proposes a novel method for analyzing similarities of protein sequences based on features generated from the hydropathy properties of amino acid sequences. At first using the hydropathy characteristics, the protein sequences are converted into fixed-dimensional feature vectors. Based on these feature vectors, we analyze nine ND5 proteins and
Yusen Zhang 0002, Xiangtian Yu
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NPS@: Network Protein Sequence Analysis
Trends in Biochemical Sciences, 2000The authors like to acknowledge financial support from CNRS, MENESR and Region Rhone-Alpes and thank all computing teams that have developed biocomputing methods for protein sequence analysis. C. Combet is the recipient of an ANRS doctoral fellowship. Thanks are due to D. Mandelman for textual improvements.
C Blanchet +2 more
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Computational Methods for Protein Sequence Analysis
Current Protocols in Protein Science, 1995AbstractThis unit is presented as a guide to addressing the issue of what to do with a protein sequence once it is obtained. A theoretical background for protein sequence analysis is provided first, followed by a discussion of matrix methods for sequence comparison ().
G, Michaels, R, Garian
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Analysis of similarity/dissimilarity of protein sequences
Proteins: Structure, Function, and Bioinformatics, 2008AbstractOn the basis of a selected pair of physicochemical properties of amino acids, we introduce a dynamic 2D graphical representation of protein sequences. Then, we introduce and compare two numerical characterizations of protein graphs as descriptors to analyze the nine ND5 proteins. The approach is simple, convenient, and fast.
Yu-Hua, Yao +5 more
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Hydrophobicity Profiles for Protein Sequence Analysis
Current Protocols in Protein Science, 1995AbstractHydrophobic interactions are a major force in protein folding and numerous hydropathy scales have been developed to quantify the relative hydrophobicity of the amino acids. Hydropathy profiles can be used to examine the surface features of proteins in order to generate hypotheses that can be confirmed experimentally.
S R, Krystek, W J, Metzler, J, Novotny
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Computer analysis of protein sequences
1974Most interesting of all of the biochemical components of living organisms are proteins and nucleic acids because of their potential for diversity in structure and function and their key positions in the evolutionary feedback system of each species. Sequence studies on these molecules have been carried out for various purposes in a number of disciplines:
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2017
ExPASy (Expert Protein Analysis System) is a Bioinformatics Resource Portal from Swiss Institute of Bioinformatics that offers Bioinformatics support like accessing scientific databases and software tools for the research in life sciences.
Kalibulla Syed Ibrahim +7 more
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ExPASy (Expert Protein Analysis System) is a Bioinformatics Resource Portal from Swiss Institute of Bioinformatics that offers Bioinformatics support like accessing scientific databases and software tools for the research in life sciences.
Kalibulla Syed Ibrahim +7 more
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The chemistry of protein sequence analysis
2000N-terminal sequence analysis by Edman chemistry continues to play an important role in the structural analysis of proteins and peptides. Improvements in the sensitivity of the method have been achieved mainly at the level of increasing the sensitivity of the on-line analysis of PTH amino acids by RP-HPLC (reverse phase high performance chromatography).
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New tools for protein sequence analysis
Trends in Biotechnology, 1990Analysis of protein sequence is an important tool in studies of both native and recombinant proteins. Novel techniques and instrumentation which facilitate determination of protein primary structure have recently been developed.
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