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Analysis of protein sequence similarity
2010 IEEE Fifth International Conference on Bio-Inspired Computing: Theories and Applications (BIC-TA), 2010This paper proposes a novel method for analyzing similarities of protein sequences based on features generated from the hydropathy properties of amino acid sequences. At first using the hydropathy characteristics, the protein sequences are converted into fixed-dimensional feature vectors. Based on these feature vectors, we analyze nine ND5 proteins and
Xiangtian Yu, Yusen Zhang
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Computer analysis of DNA and protein sequences
European Journal of Biochemistry, 1991Some recent trends in the development of theoretical methods for DNA and protein sequence analysis are reviewed, with particular emphasis on the design of new databases, motif searches, sequence alignment algorithms and applications of neural networks.
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Hydrophobicity Profiles for Protein Sequence Analysis
Current Protocols in Protein Science, 1995AbstractHydrophobic interactions are a major force in protein folding and numerous hydropathy scales have been developed to quantify the relative hydrophobicity of the amino acids. Hydropathy profiles can be used to examine the surface features of proteins in order to generate hypotheses that can be confirmed experimentally.
Jiri Novotny +2 more
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New tools for protein sequence analysis [PDF]
Trends in Biotechnology, 1990 Analysis of protein sequence is an important tool in studies of both native and recombinant proteins. Novel techniques and instrumentation which facilitate determination of protein primary structure have recently been developed.
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Protein Sequence Analysis by Proximities
2016Sequence data are widely used to get a deeper insight into biological systems. From a data analysis perspective they are given as a set of sequences of symbols with varying length. In general they are compared using nonmetric score functions. In this form the data are nonstandard, because they do not provide an immediate metric vector space and their ...
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Computational Methods for Protein Sequence Analysis
Current Protocols in Protein Science, 1995AbstractThis unit is presented as a guide to addressing the issue of what to do with a protein sequence once it is obtained. A theoretical background for protein sequence analysis is provided first, followed by a discussion of matrix methods for sequence comparison ().
George S. Michaels, Robert Garian
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Computer analysis of protein sequences
1974Most interesting of all of the biochemical components of living organisms are proteins and nucleic acids because of their potential for diversity in structure and function and their key positions in the evolutionary feedback system of each species. Sequence studies on these molecules have been carried out for various purposes in a number of disciplines:
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SEQSEE: a comprehensive program suite for protein sequence analysis
Comput. Appl. Biosci., 1994SEQSEE (SEQuence SEEker) is a multi-purpose, menu-driven suite of programs designed to provide a fully integrated, state-of-the-art package for the analysis and display of protein sequences and protein databases. It is currently configured to run on most
D. Wishart +4 more
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The chemistry of protein sequence analysis
2000N-terminal sequence analysis by Edman chemistry continues to play an important role in the structural analysis of proteins and peptides. Improvements in the sensitivity of the method have been achieved mainly at the level of increasing the sensitivity of the on-line analysis of PTH amino acids by RP-HPLC (reverse phase high performance chromatography).
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