Results 161 to 170 of about 191,213 (357)

A review of the impact of micro‐ and nanoplastics on female reproduction: What we know and gaps in knowledge

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Micro‐and nanoplastics (MNPs) are breakdown products of plastics, and humans are exposed to these particles through air, water, food, and soil. There is a growing concern that human exposure to MNPs negatively impacts health. In this review we will discuss the potential health impact of MNPs on ovarian function and the hypothalamic–pituitary ...
Sanchayana Raghuvir   +2 more
wiley   +1 more source

A Dual Action of Everolimus in Ulcerative Colitis: Blocking CLEC4E‐Driven Inflammation and Remodeling the Gut Microbiota‐Metabolite Axis

open access: yesiMetaMed, EarlyView.
Graphical abstract of the major mechanisms of Everolimus in ulcerative colitis: Everolimus, a selective mTORC1 inhibitor, protects against ulcerative colitis through a dual mechanism. First, Eve directly suppresses CLEC4E/Syk/NF‐κB signaling, thereby reducing pro‐inflammatory cytokine production and preserving intestinal barrier integrity.
Jing Chen   +6 more
wiley   +1 more source

Pim serine/threonine kinases regulate the stability of Socs-1 protein

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2002
X. P. Chen   +9 more
semanticscholar   +1 more source

Impact of organic pollutants on phenotype and gene expression in human breast cancer cells

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Human exposure to industrial chemical compounds is widespread and, although often beneficial, prolonged contact may contribute to disease development, including cancer. While many studies have shown organic pollutants (OP) are cytotoxic, few have explored how long‐term exposure alters cell phenotype.
Camila Confortin   +7 more
wiley   +1 more source

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