Results 11 to 20 of about 142,215 (332)
Inferring Compensatory Kinase Networks in Yeast using Prolog [PDF]
Signalling pathways are conserved across different species, therefore making yeast a model organism to study these via disruption of kinase activity. Yeast has 159 genes that encode protein kinases and phosphatases, and 136 of these have counterparts in humans.
arxiv +1 more source
Serine/Threonine Protein Kinase STK16 [PDF]
STK16 (Ser/Thr kinase 16, also known as Krct/PKL12/MPSK1/TSF-1) is a myristoylated and palmitoylated Ser/Thr protein kinase that is ubiquitously expressed and conserved among all eukaryotes. STK16 is distantly related to the other kinases and belongs to the NAK kinase family that has an atypical activation loop architecture.
Xinmiao Ji+6 more
openaire +2 more sources
PeSTK db a comprehensive data repository of Probiotic Serine Threonine kinases
Measurement(s) Serine threonine protein sequences of probiotic microbes Technology Type(s) Softwares uploading and downloading of sequences from various public sources Factor Type(s) Serine threonine kinases of Probiotic microbes Sample Characteristic ...
Dhanashree Lokesh+2 more
doaj +1 more source
The human oral cavity harbors approximately 1,000 microbial species, and dysbiosis of the microflora and imbalanced microbiota-host interactions drive many oral diseases, such as dental caries and periodontal disease.
Liang Ren+3 more
doaj +1 more source
Viral Serine/Threonine Protein Kinases [PDF]
ABSTRACT Phosphorylation represents one the most abundant and important posttranslational modifications of proteins, including viral proteins. Virus-encoded serine/threonine protein kinases appear to be a feature that is unique to large DNA viruses.
Thary Jacob+2 more
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Phosphorylation of the chromatin binding domain of KSHV LANA. [PDF]
The Kaposi sarcoma associated herpesvirus (KSHV) latency associated nuclear antigen (LANA) is expressed in all KSHV associated malignancies and is essential for maintenance of KSHV genomes in infected cells.
Crystal Woodard+12 more
doaj +1 more source
Mycobacterium tuberculosis Serine/Threonine Protein Kinases [PDF]
ABSTRACT The Mycobacterium tuberculosis genome encodes 11 serine/threonine protein kinases (STPKs). A similar number of two-component systems are also present, indicating that these two signal transduction mechanisms are both important in the adaptation of this bacterial pathogen to its environment. The
Robert N. Husson, Sladjana Prisic
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Molecular Basis for Ser/Thr Specificity in PKA Signaling
cAMP-dependent protein kinase (PKA) is the major receptor of the second messenger cAMP and a prototype for Ser/Thr-specific protein kinases. Although PKA strongly prefers serine over threonine substrates, little is known about the molecular basis of this
Matthias J. Knape+7 more
doaj +1 more source
Adenovirus E1A is associated with a serine/threonine protein kinase [PDF]
The adenovirus E1A proteins form stable protein complexes with a number of cellular proteins, including cyclin A and the product of the retinoblastoma susceptibility gene. We have been interested in learning about the function of proteins associated with E1A and therefore looked for an enzymatic activity present in E1A complexes.
Ed Harlow, Li-Kuo Su, C. H. Herrmann
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A framework for classification of prokaryotic protein kinases. [PDF]
BACKGROUND: Overwhelming majority of the Serine/Threonine protein kinases identified by gleaning archaeal and eubacterial genomes could not be classified into any of the well known Hanks and Hunter subfamilies of protein kinases.
Nidhi Tyagi+2 more
doaj +1 more source