Results 271 to 280 of about 209,848 (307)

PROTEIN SERINE/THREONINE KINASES

Annual Review of Biochemistry, 1987
PERSPEC TIVES AND S UMMARy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 568 CYCLIC A MP -D EP END EN T PROTEIN KINASES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 568 CYCLIC G MP -D EPENDENT PROTEIN KINASE. . . . . . . . . . . . . . . .
A M, Edelman, D K, Blumenthal, E G, Krebs   +2 more
openaire   +3 more sources

Serine/threonine protein kinases

Current Opinion in Neurobiology, 1992
Signal transduction in the nervous system is heavily dependent on the three multifunctional serine/threonine protein kinases, PKA, PKC, and CaM-KII. Recent studies have furthered our understanding of how the multiple isoforms of these kinases and their subcellular localizations, regulatory properties, and substrate determinants are important for the ...
J D, Scott, T R, Soderling
openaire   +2 more sources

Serine/threonine protein kinases in Drosophila

Trends in Genetics, 1990
The study of serine/threonine kinases in Drosophila is coming of age. Recently several kinases have been identified and their role in cell determination has been established. This review discusses these recent findings and describes the potential for genetic analyses of kinase activity and signal transduction.
E, Siegfried, L, Ambrosio, N, Perrimon
openaire   +2 more sources

Serine/Threonine Protein Kinases and Apoptosis

Experimental Cell Research, 2000
Over the past decade, our understanding of apoptosis, or programmed cell death, has increased greatly, with the identification of some of the major components of the apoptotic programme and the processes regulating their activation. Although apoptosis is an intrinsic process present in all cells, it can be regulated by extrinsic factors, including ...
T G, Cross, D, Scheel-Toellner, N V, Henriquez, E, Deacon, M, Salmon, J M, Lord   +5 more
openaire   +2 more sources

Protein Serine/Threonine Kinases

2000
The reversible phosphorylation of proteins by protein kinases is the most extensively used molecular mechanism regulating cellular functions in eukaryotes. Essentially all major cellular processes, including cell growth and differentiation, motility, metabolism, and communication between cells, are in some way regulated by protein phosphorylation (Fig.
Heierhorst, Jorg, Pearson, Richard, Horne, James, Bozinovski, Steven, Kobe, Bostjan, Kemp, Bruce E.   +5 more
openaire   +2 more sources

Protein Serine-Threonine Kinases

1992
Abstract In nature, a broad range of proteins become modified via the covalent bonding of phosphate to nucleophilic functional groups located on the side-chains of their constituent amino acids. Although numerous amino acids can be modified in this way, by far the most widespread and quantitatively significant phosphorylation events take
Peter J Kennelly, Arthur M Edelman
openaire   +1 more source

Serine-Threonine Protein Kinases of Cyanobacteria

Biochemistry (Moscow)
Protein phosphorylation is a pivotal mechanism for signal transduction, regulation of biochemical processes essential for reproduction, growth, and adaptation of organisms to changing conditions. Bacteria, which emerged more than 3.5 billion years ago, faced the need to adapt to a variety of ecological niches from the very beginning of their existence.
Anna A, Zorina, Dmitry A, Los, Oleg I, Klychnikov   +2 more
openaire   +2 more sources

Mechanisms, regulation and functions of the unfolded protein response

Nature Reviews Molecular Cell Biology, 2020
Claudio Hetz, Kezhong Zhang, Randal J Kaufman   +2 more
exaly  

Biomolecular condensates at the nexus of cellular stress, protein aggregation disease and ageing

Nature Reviews Molecular Cell Biology, 2021
Simon Alberti, Anthony A Hyman
exaly