Results 271 to 280 of about 191,213 (357)
Epigenetic Age Prediction Using N6‐Methyladenine in the Buff‐Tailed Bumblebee (Bombus terrestris)
Aging Cell, EarlyView.In bumblebees, age‐related patterns of N6‐methyladenine can be used to build accurate epigenetic clocks that are responsive to lifespan‐extending interventions, providing the first proof of concept that this epigenetic mark can be used as a biomarker of aging.
Thibaut Renard +2 more
wiley +1 more source
Dual-specificity mitogen-activated protein kinase kinases can use ADP to phosphorylate MAP kinases invitro. [PDF]
J Biol ChemJuyoux P +3 more
europepmc +1 more source
β‐Hydroxybutyrate Acts as an Exercise Mimetic to Protect the Aging Liver
Aging Cell, EarlyView.β‐hydroxybutyrate (β‐HB) acts as an exercise mimetic to protect the aging liver. In aged models, exercise‐induced β‐HB delays liver aging by reversing macrophage senescence, blocking mtDNA/cGAS‐STING‐driven inflammation, and alleviating hepatocyte lipid deposition/PANoptosis.
Ke Li +7 more
wiley +1 more source
Kinase-dependent regulation of ciliary protein transport and its implications for therapy. [PDF]
Front Mol BiosciChaya T, Ayano Y, Furukawa T.
europepmc +1 more source
Club Cells in Nasal Epithelial Repair: Insights From an IL‐13‐Induced Inflammatory Model
Allergy, EarlyView.Four inflammatory endotypes of CRSwNP, defined by eosinophil and neutrophil infiltration, show distinct patterns of basal, club, ciliated, and goblet cell expression in nasal epithelium. Using an ALI‐HNECs model, we demonstrate that IL‐13 impairs mucociliary function by promoting club‐to‐goblet cell differentiation while inhibiting club‐to‐ciliated ...
Zhi‐Qun Huang +13 more
wiley +1 more source
Correction: LKB1 suppression promotes cardiomyocyte regeneration via LKB1-AMPK-YAP axis. [PDF]
Biomol BiomedQu S +12 more
europepmc +1 more source