Results 21 to 30 of about 142,215 (332)

Correction: Correlated Mutation Analysis on the Catalytic Domains of Serine/Threonine Protein Kinases

PLoS ONE, 2009
Feng Xu, Pan Du, Hongbo Shen, Hairong Hu, Qi Wu, Jun Xie, Long Yu   +6 more
doaj   +5 more sources

Tyrosine phosphorylation of the BRI1 receptor kinase occurs via a posttranslational modification and is activated by the juxtamembrane domain

Frontiers in Plant Science, 2012
In metazoans, receptor kinases control many essential processes related to growth and development and response to the environment. The receptor kinases in plants and animals are structurally similar but evolutionarily distinct and thus while most animal ...
Man-Ho eOh, Steven D. Clouse, Steven C. Huber, Steven C. Huber   +3 more
doaj   +1 more source

ChemInform Abstract: Substrate and Docking Interactions in Serine/Threonine Protein Kinases [PDF]

ChemInform, 2007
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
John M. Humphreys, Xiaoshan Min, Tianjun Zhou, Radha Akella, Elizabeth J. Goldsmith   +4 more
openaire   +4 more sources

The serine/threonine kinase MINK1 directly regulates the function of promigratory proteins [PDF]

Journal of Cell Science, 2021
AbstractUpregulation of the developmental Wnt/planar cell polarity pathway is observed in many cancers and is associated with cancer development at early and late stages. We recently showed that PRICKLE1 and VANGL2, two core Wnt/PCP components, are overexpressed in triple negative breast cancer and associated with poor prognosis.
Daulat, Avais, Wagner, Mônica, Audebert, Stéphane, Kowalczewska, Malgorzata, Ariey-Bonnet, Jeremy, Finetti, Pascal, Bertucci, François, Camoin, Luc, Borg, Jean-Paul   +8 more
openaire   +4 more sources

Proteínas quinases: características estruturais e inibidores químicos Kinase protein: structural features and chemical inhibitors

Química Nova, 2009
Protein kinases are one of the largest protein families and they are responsible for regulation of a great number of signal transduction pathways in cells, through the phosphorylation of serine, threonine, or tyrosine residues.
Bárbara V. Silva, Bruno A. C. Horta, Ricardo Bicca de Alencastro, Angelo C. Pinto   +3 more
doaj   +1 more source

Role of serine/threonine protein phosphatase PrpN in the life cycle of Bacillus anthracis.

PLoS Pathogens, 2022
Reversible protein phosphorylation at serine/threonine residues is one of the most common protein modifications, widely observed in all kingdoms of life.
Aakriti Gangwal, Nitika Sangwan, Neha Dhasmana, Nishant Kumar, Chetkar Chandra Keshavam, Lalit K Singh, Ankur Bothra, Ajay K Goel, Andrei P Pomerantsev, Stephen H Leppla, Yogendra Singh   +10 more
doaj   +1 more source

The Subcellular Proteome of a Planctomycetes Bacterium Shows That Newly Evolved Proteins Have Distinct Fractionation Patterns

Frontiers in Microbiology, 2021
The Planctomycetes bacteria have unique cell architectures with heavily invaginated membranes as confirmed by three-dimensional models reconstructed from FIB-SEM images of Tuwongella immobilis and Gemmata obscuriglobus.
Christian Seeger, Karl Dyrhage, Mayank Mahajan, Anna Odelgard, Sara Bergström Lind, Siv G. E. Andersson   +5 more
doaj   +1 more source

A Serine/Threonine Protein Kinase fromMycobacterium tuberculosis [PDF]

European Journal of Biochemistry, 1997
Genomic DNA sequencing in the vicinity of thepstA‐1gene fromMycobacterium tuberculosisallowed us to clone, sequence and identify a gene encoding a 70‐kDa protein. The size of the protein was confirmed byin vitrocoupled transcription/translation. Its N‐terminal domain shows extensive sequence similarity with the catalytic domain of eukaryotic serine ...
Peirs, Priska, De Wit, Lucas, Braibant, Martine, Huygen, Kris, Content, Jean   +4 more
openaire   +3 more sources

STRUCTURE, ACTIVATION AND BIOLOGICAL EFFECTS OF AKT OR PROTEIN KINASE B [PDF]

Romanian Journal of Medical Practice, 2019
AKT or protein kinase B is a serine / threonine kinase that plays a crucial role in cell proliferation, survival, growth, and glucose metabolism. So far, there have been discovered 3 isoforms of AKT, the most widespread in the tissues is AKT1.
Daniela Miricescu, Alexandra Totan, Constantin Stefani, Iulia-Ioana Stănescu, Ana Maria Alexandra Stanescu, Ioana Ruxandra Rusu, Radu Radulescu, George Costin Rusu, Maria Greabu   +8 more
doaj   +1 more source

Regulation of signal duration and the statistical dynamics of kinase activation by scaffold proteins [PDF]

PLoS Comput Biol. 2008 Jun 27;4(6):e1000099, 2008
Scaffolding proteins that direct the assembly of multiple kinases into a spatially localized signaling complex are often essential for the maintenance of an appropriate biological response. Although scaffolds are widely believed to have dramatic effects on the dynamics of signal propagation, the mechanisms that underlie these consequences are not well ...
arxiv   +1 more source