Results 21 to 30 of about 191,213 (357)

Impact of Serine/Threonine Protein Kinases on the Regulation of Sporulation in Bacillus subtilis.

open access: yesFrontiers in Microbiology, 2016
Bacteria possess many kinases that catalyze phosphorylation of proteins on diverse amino acids including arginine, cysteine, histidine, aspartate, serine, threonine and tyrosine.
Frédérique ePompeo   +2 more
doaj   +1 more source

Tyrosine phosphorylation regulates RIPK1 activity to limit cell death and inflammation

open access: yesNature Communications, 2022
Receptor-interacting serine/threonine-protein kinase 1 (RIPK1) is an important regulator of cell death pathways during embryogenesis and in infection/inflammation.
Hailin Tu   +4 more
doaj   +1 more source

In Silico Prediction of the Phosphorylation of NS3 as an Essential Mechanism for Dengue Virus Replication and the Antiviral Activity of Quercetin

open access: yesBiology, 2021
Dengue virus infection is a global health problem for which there have been challenges to obtaining a cure. Current vaccines and anti-viral drugs can only be narrowly applied in ongoing clinical trials.
Lamya Alomair   +3 more
doaj   +1 more source

Discovery of a Selective NEK6 Kinase Inhibitor by Virtual Screening

open access: yesProceedings, 2019
NIMA-related kinases (Neks) are a conserved serine/threonine protein kinase family related tocell cycle progression and cell division [...]
Benedetta Righino   +8 more
doaj   +1 more source

Expression of Novel Kinase MAP3K19 in Various Cancers and Survival Correlations

open access: yesFrontiers in Bioscience-Landmark, 2022
Mitogen Activated Protein (MAP) kinases are a category of serine/threonine kinases that have been demonstrated to regulate intracellular events including stress responses, developmental processes, and cancer progression Although many MAP kinases have ...
Khoa Nguyen   +20 more
doaj   +1 more source

Correlated mutation analysis on the catalytic domains of serine/threonine protein kinases. [PDF]

open access: yesPLoS ONE, 2009
BACKGROUND:Protein kinases (PKs) have emerged as the largest family of signaling proteins in eukaryotic cells and are involved in every aspect of cellular regulation.
Feng Xu   +6 more
doaj   +1 more source

Phosphoproteomics analysis of a clinical Mycobacterium tuberculosis Beijing isolate: Expanding the mycobacterial phosphoproteome catalogue

open access: yesFrontiers in Microbiology, 2015
Reversible protein phosphorylation, regulated by protein kinases and phosphatases, mediates a switch between protein activity and cellular pathways that contribute to a large number of cellular processes.
Suereta eFortuin   +8 more
doaj   +1 more source

Case report: A novel frameshift mutation in BRSK2 causes autism in a 16-year old Chinese boy

open access: yesFrontiers in Psychiatry, 2023
Serine/threonine protein kinases are involved in axon formation and neuronal polarization and have recently been implicated in autism spectrum disorder (ASD) and neurodevelopmental disorders (NDD).
Yu Hu   +18 more
doaj   +1 more source

Protein serine/threonine kinases (PKA, PKC and CaMKII) involved in ischemic brain pathology.

open access: yesActa Neurobiologiae Experimentalis, 1996
The protein serine/threonine kinases which are highly expressed in the central nervous system (CNS) are severely affected by brain ischemia. Irrespective of substantial differences among the particular members of this group of kinases, their responses to
K. Domanska-Janik
semanticscholar   +1 more source

Structural basis for ALK2/BMPR2 receptor complex signaling through kinase domain oligomerization

open access: yesNature Communications, 2021
Bone morphogenetic protein (BMP) receptors are single pass transmembrane serine/threonine kinases that form tetrameric complexes comprised of two type I and two type II BMP receptors.
Christopher Agnew   +10 more
doaj   +1 more source

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