Results 21 to 30 of about 133,461 (307)
The serine/threonine kinase MINK1 directly regulates the function of promigratory proteins [PDF]
Journal of Cell Science, 2021 AbstractUpregulation of the developmental Wnt/planar cell polarity pathway is observed in many cancers and is associated with cancer development at early and late stages. We recently showed that PRICKLE1 and VANGL2, two core Wnt/PCP components, are overexpressed in triple negative breast cancer and associated with poor prognosis.
Daulat, Avais +8 more
openaire +4 more sources
Role of serine/threonine protein phosphatase PrpN in the life cycle of Bacillus anthracis.
PLoS Pathogens, 2022 Reversible protein phosphorylation at serine/threonine residues is one of the most common protein modifications, widely observed in all kingdoms of life.
Aakriti Gangwal +10 more
doaj +1 more source
ChemInform Abstract: Substrate and Docking Interactions in Serine/Threonine Protein Kinases [PDF]
ChemInform, 2007 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
John M. Humphreys +4 more
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Frontiers in Microbiology, 2021 The Planctomycetes bacteria have unique cell architectures with heavily invaginated membranes as confirmed by three-dimensional models reconstructed from FIB-SEM images of Tuwongella immobilis and Gemmata obscuriglobus.
Christian Seeger +5 more
doaj +1 more source
A Serine/Threonine Protein Kinase fromMycobacterium tuberculosis [PDF]
European Journal of Biochemistry, 1997 Genomic DNA sequencing in the vicinity of thepstA‐1gene fromMycobacterium tuberculosisallowed us to clone, sequence and identify a gene encoding a 70‐kDa protein. The size of the protein was confirmed byin vitrocoupled transcription/translation. Its N‐terminal domain shows extensive sequence similarity with the catalytic domain of eukaryotic serine ...
Peirs, Priska +4 more
openaire +3 more sources
Frontiers in Microbiology, 2014 Bacteria possess protein serine/threonine and tyrosine kinases which resemble eukaryal kinases in their capacity to phosphorylate multiple substrates. We hypothesized that the analogy might extend further, and bacterial kinases may also undergo mutual ...
Lei eShi +7 more
doaj +1 more source
STRUCTURE, ACTIVATION AND BIOLOGICAL EFFECTS OF AKT OR PROTEIN KINASE B [PDF]
Romanian Journal of Medical Practice, 2019 AKT or protein kinase B is a serine / threonine kinase that plays a crucial role in cell proliferation, survival, growth, and glucose metabolism. So far, there have been discovered 3 isoforms of AKT, the most widespread in the tissues is AKT1.
Daniela Miricescu +8 more
doaj +1 more source
Bacterial Serine/Threonine Protein Kinases in Host-Pathogen Interactions [PDF]
Journal of Biological Chemistry, 2014 In bacterial pathogenesis, monitoring and adapting to the dynamically changing environment in the host and an ability to disrupt host immune responses are critical. The virulence determinants of pathogenic bacteria include the sensor/signaling proteins of the serine/threonine protein kinase (STPK) family that have a dual role of sensing the environment
Canova, Marc, Molle, Virginie
openaire +3 more sources
Tyrosine phosphorylation regulates RIPK1 activity to limit cell death and inflammation
Nature Communications, 2022 Receptor-interacting serine/threonine-protein kinase 1 (RIPK1) is an important regulator of cell death pathways during embryogenesis and in infection/inflammation.
Hailin Tu +4 more
doaj +1 more source