Association between intrinsic disorder and serine/threonine phosphorylation in Mycobacterium tuberculosis [PDF]
PeerJ, 2015 Serine/threonine phosphorylation is an important mechanism that is involved in the regulation of protein function. In eukaryotes, phosphorylation occurs predominantly in intrinsically disordered regions of proteins.
Gajinder Pal Singh
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Circumventing embryonic lethality with Lcmt1 deficiency: generation of hypomorphic Lcmt1 mice with reduced protein phosphatase 2A methyltransferase expression and defects in insulin signaling. [PDF]
, 2013 Protein phosphatase 2A (PP2A), the major serine/threonine phosphatase in eukaryotic cells, is a heterotrimeric protein composed of structural, catalytic, and targeting subunits.
Clarke, Steven G +3 more
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PeSTK db a comprehensive data repository of Probiotic Serine Threonine kinases
Scientific Data, 2022 Measurement(s) Serine threonine protein sequences of probiotic microbes Technology Type(s) Softwares uploading and downloading of sequences from various public sources Factor Type(s) Serine threonine kinases of Probiotic microbes Sample Characteristic ...
Dhanashree Lokesh +2 more
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Frontiers in Cellular and Infection Microbiology, 2022 The human oral cavity harbors approximately 1,000 microbial species, and dysbiosis of the microflora and imbalanced microbiota-host interactions drive many oral diseases, such as dental caries and periodontal disease.
Liang Ren +3 more
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Serine/Threonine Protein Kinase STK16 [PDF]
International Journal of Molecular Sciences, 2019 STK16 (Ser/Thr kinase 16, also known as Krct/PKL12/MPSK1/TSF-1) is a myristoylated and palmitoylated Ser/Thr protein kinase that is ubiquitously expressed and conserved among all eukaryotes. STK16 is distantly related to the other kinases and belongs to the NAK kinase family that has an atypical activation loop architecture.
Junjun Wang +3 more
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Viral Serine/Threonine Protein Kinases [PDF]
Journal of Virology, 2011 ABSTRACT Phosphorylation represents one the most abundant and important posttranslational modifications of proteins, including viral proteins. Virus-encoded serine/threonine protein kinases appear to be a feature that is unique to large DNA viruses.
Thary, Jacob +2 more
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Phosphorylation of the chromatin binding domain of KSHV LANA. [PDF]
PLoS Pathogens, 2012 The Kaposi sarcoma associated herpesvirus (KSHV) latency associated nuclear antigen (LANA) is expressed in all KSHV associated malignancies and is essential for maintenance of KSHV genomes in infected cells.
Crystal Woodard +12 more
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The Serine/Threonine Protein Kinase (Akt)/ Protein Kinase B (PkB) Signaling Pathway in Breast Cancer [PDF]
, 2020 According to statistical data published in 2019, breast cancer is among the leading causes of death in women worldwide. The serine/threonine kinase (AKT) or protein kinase B (PkB) signaling pathway is activated by phosphorylation processes, which further
Bratu, Ovidiu Gabriel +8 more
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Molecular Basis for Ser/Thr Specificity in PKA Signaling
Cells, 2020 cAMP-dependent protein kinase (PKA) is the major receptor of the second messenger cAMP and a prototype for Ser/Thr-specific protein kinases. Although PKA strongly prefers serine over threonine substrates, little is known about the molecular basis of this
Matthias J. Knape +7 more
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A framework for classification of prokaryotic protein kinases. [PDF]
PLoS ONE, 2010 BACKGROUND: Overwhelming majority of the Serine/Threonine protein kinases identified by gleaning archaeal and eubacterial genomes could not be classified into any of the well known Hanks and Hunter subfamilies of protein kinases.
Nidhi Tyagi +2 more
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