Results 31 to 40 of about 133,461 (307)
The serine‐threonine kinase PIM3 is an aldosterone‐regulated protein in the distal nephron [PDF]
Physiological Reports, 2019 The mineralocorticoid hormone aldosterone plays a crucial role in the control of Na+ and K+ balance, blood volume, and arterial blood pressure, by acting in the aldosterone-sensitive distal nephron (ASDN) and stimulating a complex transcriptional, translational, and cellular program. Because the complexity of the aldosterone response is still not fully
Spirli, Alessia +8 more
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Biochemical characterization of a family of serine/threonine protein kinases regulated by tyrosine and serine/threonine phosphorylations. [PDF]
Journal of Biological Chemistry, 1991 Mitogen-activated protein kinase (p42mapk) becomes transiently activated after treatment of serum-starved murine Swiss 3T3 cells or EL4 thymocytes with a diversity of mitogens. Similarly, a meiosis-activated protein kinase (p44mpk) becomes stimulated during maturation of sea star oocytes induced by 1-methyladenine.
A J Rossomando +5 more
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Biology, 2021 Dengue virus infection is a global health problem for which there have been challenges to obtaining a cure. Current vaccines and anti-viral drugs can only be narrowly applied in ongoing clinical trials.
Lamya Alomair +3 more
doaj +1 more source
Discovery of a Selective NEK6 Kinase Inhibitor by Virtual Screening
Proceedings, 2019 NIMA-related kinases (Neks) are a conserved serine/threonine protein kinase family related tocell cycle progression and cell division [...]
Benedetta Righino +8 more
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Expression of Novel Kinase MAP3K19 in Various Cancers and Survival Correlations
Frontiers in Bioscience-Landmark, 2022 Mitogen Activated Protein (MAP) kinases are a category of serine/threonine kinases that have been demonstrated to regulate intracellular events including stress responses, developmental processes, and cancer progression Although many MAP kinases have ...
Khoa Nguyen +20 more
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Frontiers in Microbiology, 2015 Reversible protein phosphorylation, regulated by protein kinases and phosphatases, mediates a switch between protein activity and cellular pathways that contribute to a large number of cellular processes.
Suereta eFortuin +8 more
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Structural basis for ALK2/BMPR2 receptor complex signaling through kinase domain oligomerization
Nature Communications, 2021 Bone morphogenetic protein (BMP) receptors are single pass transmembrane serine/threonine kinases that form tetrameric complexes comprised of two type I and two type II BMP receptors.
Christopher Agnew +10 more
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Case report: A novel frameshift mutation in BRSK2 causes autism in a 16-year old Chinese boy
Frontiers in Psychiatry, 2023 Serine/threonine protein kinases are involved in axon formation and neuronal polarization and have recently been implicated in autism spectrum disorder (ASD) and neurodevelopmental disorders (NDD).
Yu Hu +18 more
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Genome-wide survey of putative Serine/Threonine protein kinases in cyanobacteria
BMC Genomics, 2007 Background Serine/threonine kinases (STKs) have been found in an increasing number of prokaryotes, showing important roles in signal transduction that supplement the well known role of two-component system.
Guan Xiangyu +5 more
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Life, 2021 Protein phosphorylation is one of the most widely observed and important post-translational modification (PTM) processes. Protein phosphorylation is regulated by protein kinases, each of which covalently attaches a phosphate group to an amino acid side ...
Seung-Hyeon Seok
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