Results 51 to 60 of about 138,869 (211)

Numerous Serine/Threonine Kinases Affect Blood Cell Homeostasis in Drosophila melanogaster

Cells
Blood cells in Drosophila serve primarily innate immune responses. Various stressors influence blood cell homeostasis regarding both numbers and the proportion of blood cell types.
Sebastian Deichsel, Bernd M. Gahr, Helena Mastel, Anette Preiss, Anja C. Nagel   +4 more
doaj   +1 more source

Supplementary Legends from Maternal Embryonic Leucine Zipper Kinase/Murine Protein Serine-Threonine Kinase 38 Is a Promising Therapeutic Target for Multiple Cancers

, 2023
Daniel H.D. Gray, Adrian M. Jubb, Deborah Hogue, Patrick F. Dowd, Noelyn M. Kljavin, Sothy Yi, Wei Bai, Gretchen Frantz, Zemin Zhang, Hartmut Koeppen, Frédéric J. de Sauvage, David P. Davis   +11 more
openalex   +1 more source

Serine/Threonine-Protein Kinase D2 [PDF]

, 2020
National Cancer Institute
openalex   +1 more source

NM23-H1 Tumor Suppressor Physically Interacts with Serine-Threonine Kinase Receptor-associated Protein, a Transforming Growth Factor-β (TGF-β) Receptor-interacting Protein, and Negatively Regulates TGF-β Signaling [PDF]

, 2007
Hyun‐A Seong, Haiyoung Jung, Hyunjung Ha   +2 more
openalex   +1 more source

Genome-wide evolutionary analysis of TKL_CTR1-DRK-2 gene family and functional characterization reveals that TaCTR1 positively regulates flowering time in wheat

BMC Genomics
Background Flowering time has an important effect on regional adaptation and yields for crops. The tyrosine kinase-like (TKL) gene family is widely existed and participates in many biological processes in plants.
Peisen S. Su, Jingyu Li, Dongtian Zang, Zhiyu Wang, Yangyang Wu, Shatong Chi, Fanting Sun, Yufei Niu, Xuewen Hua, Jun Yan, Wenyang Ge   +10 more
doaj   +1 more source

The 14-3-3 Protein Family, Beyond the Kinases and Phosphatases

Kinases and Phosphatases
Eukaryotic phosphorylation of serine and threonine residues is a central regulatory mechanism in cell signalling, carried out by more than 500 kinases and a diverse array of phosphatases.
Exequiel E. Barrera, Marina Uhart, Diego M. Bustos   +2 more
doaj   +1 more source

From the biology of PP2A to the PADs for therapy of Hematologic malignancies

Frontiers in Oncology, 2015
Over the past decades, an emerging role of phosphates in the pathogenesis of hematologic malignancies and solid tumors has been established. The tumor suppressor Protein phosphatase 2A (PP2A) belongs to the serine-threonine phosphatases family and ...
Maria eCiccone, George eCalin, Danilo ePerrotti   +2 more
doaj   +1 more source

Functional Roles of p38 Mitogen-Activated Protein Kinase in Macrophage-Mediated Inflammatory Responses

Mediators of Inflammation, 2014
Inflammation is a natural host defensive process that is largely regulated by macrophages during the innate immune response. Mitogen-activated protein kinases (MAPKs) are proline-directed serine and threonine protein kinases that regulate many ...
Yanyan Yang, Seung Cheol Kim, Tao Yu, Young-Su Yi, Man Hee Rhee, Gi-Ho Sung, Byong Chul Yoo, Jae Youl Cho   +7 more
doaj   +1 more source

MicroRNA miR-212-5p Regulates the MEK/ERK Signaling Pathway by Targeting A-Raf proto-oncogene serine/threonine-protein kinase (ARAF) to Regulate Cowshed PM2.5-Induced NR8383 Apoptosis [PDF]

, 2023
Ke Sun, Yize Sun, Yunna Jia, Xinran Duan, Zhenhua Ma, Xiqing Zhang, Lixia Wang, Yanbin Zhu, Yunhang Gao, Wangdui Basang   +9 more
openalex   +1 more source

Serine Threonine Kinase Receptor-Associated Protein Deficiency Impairs Mouse Embryonic Stem Cells Lineage Commitment Through CYP26A1-Mediated Retinoic Acid Homeostasis [PDF]

, 2018
Lin Jin, Chenbei Chang, Kevin M. Pawlik, Arunima Datta, Larry M. Johnson, Trung Vu, Joseph L. Napoli, Pran K. Datta   +7 more
openalex   +1 more source