Results 51 to 60 of about 261,891 (384)

Identification of sites phosphorylated by the vaccinia virus B1R kinase in viral protein H5R [PDF]

, 2000
Background: Vaccinia virus gene B1R encodes a erine/threonine protein kinase. In vitro this protein kinase phosphorylates ribosomal proteins Sa and S2 and vaccinia virus protein H5R, proteins that become phosphorylated during infection.
Beaud, G., Brown, N.G., Hardie, G., Leader, D.P., Morrice, D.N.   +4 more
core   +3 more sources

The serine‐threonine kinase PIM3 is an aldosterone‐regulated protein in the distal nephron [PDF]

Physiological Reports, 2019
The mineralocorticoid hormone aldosterone plays a crucial role in the control of Na+ and K+ balance, blood volume, and arterial blood pressure, by acting in the aldosterone-sensitive distal nephron (ASDN) and stimulating a complex transcriptional, translational, and cellular program. Because the complexity of the aldosterone response is still not fully
Spirli, Alessia, Cheval, Lydie, Debonneville, Anne, Penton, David, Ronzaud, Caroline, Maillard, Marc, Doucet, Alain, Loffing, Johannes, Staub, Olivier   +8 more
openaire   +5 more sources

Phosphorylation is required for the pathogen defense function of the Arabidopsis PEN3 ABC transporter. [PDF]

, 2017
The Arabidopsis PEN3 ABC transporter accumulates at sites of pathogen detection, where it is involved in defense against a number of pathogens. Perception of PAMPs by pattern recognition receptors initiates recruitment of PEN3 and also leads to PEN3 ...
Somerville, Shauna, Underwood, William
core   +1 more source

Toxoplasma and Plasmodium protein kinases: roles in invasion and host cell remodelling [PDF]

, 2011
Some apicomplexan parasites have evolved distinct protein kinase families to modulate host cell structure and function. Toxoplasma gondii rhoptry protein kinases and pseudokinases are involved in virulence and modulation of host cell signalling.
Abdi, Agarwal, Allen, Anamika, Behnke, Billker, Billker, Bishop, Blethrow, Bracchi-Ricard, Bradley, Brian M. Cooke, Butcher, Carruthers, Carvalho, Christian Doerig, Cooke, Cooke, Coppi, Dalpke, Daniel C. Lim, Dar, Doerig, Doerig, Doerig, Dorin, Dorin, Dorin, Droucheau, El Hajj, Fennell, Fentress, Gilbert, Green, Gueirard, Halbert, Hanks, Huse, Hutti, Ishino, Jensen, Jeroen P.J. Saeij, Kafsack, Kannan, Kato, Khaminets, Khan, Khan, Khan, Kieschnick, Kun, Kuo, Labesse, Ling, Lodoen, Lourido, Luder, Manning, Martens, Melzer, Nagamune, Nunes, Nunes, Ojo, Ong, Parsons, Peixoto, Pernas, Qiu, Reese, Reese, Reese, Reininger, Reininger, Reininger, Rosenberg, Rosowski, Saeij, Saeij, Scheibel, Schneider, Shiels, Sicard, Singh, Singh, Solyakov, Sopko, Steinfeldt, Sugi, Suss-Toby, Taylor, Taylor, Tewari, Vaid, van de Sand, Ward, Ward, Wernimont, Wernimont, Xu, Yamamoto, Yasukawa, Zeqiraj, Zeqiraj, Zhao, Zhao   +105 more
core   +2 more sources

Salt-inducible kinases (SIKs) regulate TGFβ-mediated transcriptional and apoptotic responses [PDF]

, 2020
The signalling pathways initiated by members of the transforming growth factor-β (TGFβ) family of cytokines control many metazoan cellular processes, including proliferation and differentiation, epithelial-mesenchymal transition (EMT) and apoptosis. TGFβ
A Rojas-Fernandez, A Woods, AR Ramjaun, AY Hsing, B Bierie, B Ozdamar, B-C Kim, BR Binder, C Allan, CJ David, CS Hill, DB Shackelford, EC Connolly, FA Ran, G Avery-Cooper, G Rena, G Rosti, GD Cuny, GJ Inman, GJ Inman, GM Keating, H Ikushima, J Massagué, J Massagué, J Massaous, J Ozanne, J Song, J Vogt, J Xu, JF Callahan, JL Wrana, JM Lizcano, Joan Massagué, JY Altarejos, K Clark, KA Brown, KJ Livak, LC Spender, LC Spender, M Abe, M Kowanetz, M Tojo, MO Li, MR Keeton, NJ Bright, P Lönn, PH Lin, PK Datta, PM Siegel, RJ Akhurst, RJ Akhurst, S DaCosta Byfield, S Dennler, S Edlund, S Strickson, SA Hawley, T Sonntag, TB Sundberg, Y Drabsch, Y Liu, Y Shi, Y Yang, Y Zhang, Y Zhang   +63 more
core   +2 more sources

Phosphoproteomics analysis of a clinical Mycobacterium tuberculosis Beijing isolate: Expanding the mycobacterial phosphoproteome catalogue

Frontiers in Microbiology, 2015
Reversible protein phosphorylation, regulated by protein kinases and phosphatases, mediates a switch between protein activity and cellular pathways that contribute to a large number of cellular processes.
Suereta eFortuin, Gisele eTomazella, Naga eNagayaryan, Samantha eSampson, Nicolaas eGey van Pittius, Nelson Da Cruz Soares, Harald eWiker, Gustavo eDe Souza, Robin Mark Warren   +8 more
doaj   +1 more source

Phospho.ELM:a database of experimentally verified phosphorylation sites in eukaryotic proteins [PDF]

, 2004
BACKGROUND: Post-translational phosphorylation is one of the most common protein modifications. Phosphoserine, threonine and tyrosine residues play critical roles in the regulation of many cellular processes.
Blom, Nikolaj, Cameron, Scott, Diella, Francesca, Gemünd, Christine, Gibson, Toby J., Kuster, Bernhard, Linding, Rune, Sicheritz-Pontén, Thomas, Via, Allegra   +8 more
core   +4 more sources

Case report: A novel frameshift mutation in BRSK2 causes autism in a 16-year old Chinese boy

Frontiers in Psychiatry, 2023
Serine/threonine protein kinases are involved in axon formation and neuronal polarization and have recently been implicated in autism spectrum disorder (ASD) and neurodevelopmental disorders (NDD).
Yu Hu, Yu Hu, Miao Li, Miao Li, Yanmei Shen, Tianyun Wang, Tianyun Wang, Tianyun Wang, Tianyun Wang, Qiwei Liu, Qiwei Liu, Qiwei Liu, Zhonghua Lu, Zhonghua Lu, Hong Wang, Hong Wang, Xuerong Luo, Lixin Yang, Lixin Yang   +18 more
doaj   +1 more source

New insights into the mechanisms of phytochrome-cryptochrome coaction. [PDF]

, 2018
Contents Summary 547 I. Introduction 547 II. Phytochromes mediate light-induced transcription of BICs to inactivate cryptochromes 548 III. PPKs phosphorylate light-signaling proteins and histones to affect plant development 548 IV.
Ahmad, Bourbousse, Bourbousse, Casas-Mollano, Cashmore, Devlin, Guo, Hoecker, Huang, Hughes, Huq, Ichikawa, Jang, Leivar, Lian, Liu, Liu, Liu, Lu, Ma, Martinez-Garcia, Mas, Mohr, Ni, Ni, Ni, Nusinow, Pedmale, Quail, Rosenfeldt, Saijo, Sang, Sellaro, Shalitin, Sheerin, Su, Su, Tessadori, Tessadori, Wang, Wang, Wang, Wang, Wang, Weidler, Yang, Zheng, Zuo   +47 more
core   +1 more source

Structural basis for ALK2/BMPR2 receptor complex signaling through kinase domain oligomerization

Nature Communications, 2021
Bone morphogenetic protein (BMP) receptors are single pass transmembrane serine/threonine kinases that form tetrameric complexes comprised of two type I and two type II BMP receptors.
Christopher Agnew, Pelin Ayaz, Risa Kashima, Hanna S. Loving, Prajakta Ghatpande, Jennifer E. Kung, Eric S. Underbakke, Yibing Shan, David E. Shaw, Akiko Hata, Natalia Jura   +10 more
doaj   +1 more source