Results 51 to 60 of about 220,067 (314)
Nanobody-based VSR7 tracing shows clathrin-dependent TGN to Golgi recycling
Nature Communications, 2023 Receptor-mediated transport of soluble proteins is nature’s key to empowering eukaryotic cells to access a plethora of macromolecules, either by direct accumulation or as products from resulting biochemical pathways.
Xiaoyu Shao, Hao Xu, Peter Pimpl
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Cis-elements of protein transport to the plant vacuoles [PDF]
, 2017 Vacuolar proteins are synthesized and translocated into the endoplasmic reticulum and transported to the vacuoles through the secretory pathway.
Matsuoka, Ken, Neuhaus, Jean-Marc
core
Eimeria tenella protein trafficking: differential regulation of secretion versus surface tethering during the life cycle [PDF]
, 2017 Eimeria spp. are intracellular parasites that have a major impact on poultry. Effective live vaccines are available and the development of reverse genetic technologies has raised the prospect of using Eimeria spp.
Blake, D P +4 more
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Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Frontiers in Plant Science, 2012 The specific recognition of miRNAs by Argonaute (AGO) proteins, the effector proteins of the RNA-induced silencing complex, constitutes the final step of the biogenesis of miRNAs and is crucial for their target interaction.
Christoph J Thieme +3 more
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Sorting and Targeting of Melanosomal Membrane Proteins: Signals, Pathways, and Mechanisms [PDF]
Pigment Cell Research, 2000 Newly synthesized melanosomal proteins, like many other cellular proteins, traverse through a series of intracellular compartments en route to melanosomes. Entry and exit of proteins through these compartments is orchestrated by cellular sorting machinery that recognize specific sorting signals.
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Concepts of protein sorting or targeting signals and membrane topology in undergraduate teaching* [PDF]
Biochemistry and Molecular Biology Education, 2005 AbstractThe process of protein biogenesis culminates in its correct targeting to specific subcellular locations where it serves a function. Contemporary molecular and cell biology investigations often involve the exogenous expression of epitope‐ or fluorescent protein‐tagged recombinant molecules as well as subsequent analysis of protein‐protein ...
Bor Luen, Tang, Felicia Yu Hsuan, Teng
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Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
PLoS Pathogens, 2017 Mitochondria cannot form de novo but require mechanisms that mediate their inheritance to daughter cells. The parasitic protozoan Trypanosoma brucei has a single mitochondrion with a single-unit genome that is physically connected across the two ...
Sandro Käser +10 more
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A distinct sortase SrtB anchors and processes a streptococcal adhesin AbpA with a novel structural property. [PDF]
, 2016 Surface display of proteins by sortases in Gram-positive bacteria is crucial for bacterial fitness and virulence. We found a unique gene locus encoding an amylase-binding adhesin AbpA and a sortase B in oral streptococci.
Haase, EM +6 more
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