Results 241 to 250 of about 6,635,393 (306)

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

A Novel SIL1 Variant (p.E342K) Associated with Marinesco-Sjögren Syndrome Impairs Protein Stability and Function. [PDF]

Int J Mol Sci
Ruggieri AG, Marinakis NM, Amodei L, Potenza F, Kampouraki A, Tilemis FN, Pietrangelo L, Viele M, Di Marco F, Del Boccio P, Di Cintio F, Selenti N, Valari M, Federici L, Miele AE, Sallese M, Makrythanasis P.   +16 more
europepmc   +1 more source

Genetic mapping of novel QTL for seed protein stability in food-grade soybean (Glycine max). [PDF]

Theor Appl Genet
Mitchell AA, Lin F, Ye H, Vuong T, Wen Z, Tessema B, Laurenz R, Thada Magar R, Nguyen HT, Wang D.   +9 more
europepmc   +1 more source

<i>TSC2</i> GAP Domain V1646Cfs*7 Variant Alters Protein Stability and Interaction Networks in Tuberous Sclerosis Complex. [PDF]

Neurol Genet
Utami KH, Han VX, Mohammad Yusof NAB, Ramaswamy Y, Feng J, Tay SKH, Langley SR, Pouladi MA.   +7 more
europepmc   +1 more source

The miR164e-NAC32 module orchestrates maize plant height via post-translational regulation of DELLA protein stability. [PDF]

Plant Commun
Peng C, Zhao X, Xiao J, Zhong X, Chen L, He Y, Li Z, Zhou Y, Duan L.   +8 more
europepmc   +1 more source

Kap1 Regulates Protein Stability of Nanog by Interfering with Fbxw8-Dependent Ubiquitination. [PDF]

Int J Stem Cells
Moon HJ, Lee N, Lee BS, Park MS, Jung YJ, Kim YS, Kim JH.   +6 more
europepmc   +1 more source

Protocol for monitoring the stability of transcription factor EB using global protein stability assay. [PDF]

STAR Protoc
Wang B, Zhao Y, Li R, Li X, Dong C, Mi W, Wang X.   +6 more
europepmc   +1 more source

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Protein kinetic stability

Biophysical Chemistry, 2010
The relevance of protein stability for biological function and molecular evolution is widely recognized. Protein stability, however, comes in two flavours: thermodynamic stability, which is related to a low amount of unfolded and partially-unfolded states in equilibrium with the native, functional protein; kinetic stability, which is related to a high ...
José Manuel Sánchez Ruiz
exaly   +3 more sources

Stabilization centers and protein stability

Theoretical Chemistry Accounts: Theory, Computation, and Modeling (Theoretica Chimica Acta), 2001
The well-balanced stability of protein structures allows large-scale fluctuations, which are indispensable in many biochemical functions, ensures the long-term persistence of the equilibrium structure and it regulates the degradation of proteins to provide amino acids for biosynthesis.
Á. Simon, Z. Dosztányi, C. Magyar, G. Szirtes, É. Rajnavölgyi, I. Simon   +5 more
openaire   +1 more source

Thermal stability of proteins

Archives of Biochemistry and Biophysics, 1973
Abstract The maximum melting points of 14 proteins in respect to pH are reported, the correlation coefficient between the hydrophobic index and the melting point was +0.622, and that between the average residue volumes and the melting points was +0.960.
H B, Bull, K, Breese
openaire   +2 more sources