Results 11 to 20 of about 315,126 (303)
EasyModel: a user-friendly web-based interface based on MODELLER
Scientific Reports, 2023 Three-dimensional protein structures are invaluable sources of information for the functional annotation of protein molecules. Describing the function of a protein sequence is one of the most common problems in biology.
Seyed Shahriar Arab, Alireza Dantism
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Ultrasonics Sonochemistry, 2023 The effects of air thawing (AT), water immersion thawing (WT), microwave thawing (MT) and ultrasound combined with slightly acidic electrolyzed water thawing (UST) on the myofibrillar protein (MP) properties (surface hydrophobicity, solubility, turbidity,
Dewei Kong +8 more
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Prediction of Protein Tertiary Structure via Regularized Template Classification Techniques
Molecules, 2020 We discuss the use of the regularized linear discriminant analysis (LDA) as a model reduction technique combined with particle swarm optimization (PSO) in protein tertiary structure prediction, followed by structure refinement based on singular value ...
Óscar Álvarez-Machancoses +2 more
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Evaluating Autoencoder-Based Featurization and Supervised Learning for Protein Decoy Selection
Molecules, 2020 Rapid growth in molecular structure data is renewing interest in featurizing structure. Featurizations that retain information on biological activity are particularly sought for protein molecules, where decades of research have shown that indeed ...
Fardina Fathmiul Alam +2 more
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BMC Bioinformatics, 2023 Background CRISPR-Cas-Docker is a web server for in silico docking experiments with CRISPR RNAs (crRNAs) and Cas proteins. This web server aims at providing experimentalists with the optimal crRNA-Cas pair predicted computationally when prokaryotic ...
Ho-min Park +7 more
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De novo protein structure prediction using ultra-fast molecular dynamics simulation. [PDF]
PLoS ONE, 2018 Modern genomics sequencing techniques have provided a massive amount of protein sequences, but experimental endeavor in determining protein structures is largely lagging far behind the vast and unexplored sequences.
Ngaam J Cheung, Wookyung Yu
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Protein secondary structure: Entropy, correlations and prediction [PDF]
, 2003 Is protein secondary structure primarily determined by local interactions between residues closely spaced along the amino acid backbone, or by non-local tertiary interactions?
Brenner, Steven E., Crooks, Gavin E.
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CASP11--An Evaluation of a Modular BCL::Fold-Based Protein Structure Prediction Pipeline. [PDF]
PLoS ONE, 2016 In silico prediction of a protein's tertiary structure remains an unsolved problem. The community-wide Critical Assessment of Protein Structure Prediction (CASP) experiment provides a double-blind study to evaluate improvements in protein structure ...
Axel W Fischer +7 more
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Utilizing Protein Structure to Identify Non-Random Somatic Mutations [PDF]
, 2013 Motivation: Human cancer is caused by the accumulation of somatic mutations in tumor suppressors and oncogenes within the genome. In the case of oncogenes, recent theory suggests that there are only a few key "driver" mutations responsible for ...
Cheng, Yuwei +4 more
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A Hierarchical Approach to Protein Molecular Evolution [PDF]
, 1999 Biological diversity has evolved despite the essentially infinite complexity of protein sequence space. We present a hierarchical approach to the efficient searching of this space and quantify the evolutionary potential of our approach with Monte Carlo ...
Crameri +30 more
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