Results 71 to 80 of about 317,356 (295)

Structural role of the tyrosine residues of cytochrome c [PDF]

open access: yes, 1982
The tertiary structures of horse, tuna, Neurospora crassa, horse [Hse65,Leu67]- and horse [Hse65,Leu74]-cytochromes c were studied with high-resolution 1H n.m.r. spectroscopy.
Boon, Peter J.   +7 more
core  

Structural classification of biotin carboxyl carrier proteins [PDF]

open access: yes, 2012
We gathered primary and tertiary structures of acyl-CoA carboxylases from public databases, and established that members of their biotin carboxylase (BC) and biotin carboxyl carrier protein (BCCP) domains occur in one family each and that members of ...
Cantu, David   +4 more
core   +3 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Analysis of ORF5 protein signifies its importance in Norway rat Hepatitis E virus [PDF]

open access: yesNetwork Biology, 2022
Hepatitis E virus (HEV) is the chief cause of hepatitis E (inflammation of liver) across the globe. The Norway rat HEV genome consists of six open reading frames (ORFs), i.e., ORF1, ORF2, ORF3, ORF4, ORF5 and ORF5.
Zoya Shafat   +2 more
doaj  

Large-scale identification of coevolution signals across homo-oligomeric protein interfaces by Direct Coupling Analysis

open access: yes, 2017
Proteins have evolved to perform diverse cellular functions, from serving as reaction catalysts to coordinating cellular propagation and development.
Lovis, Shalini John   +5 more
core   +2 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Structural, functional and phylogenetic characterization of basic fatty acid binding protein 10 (Fabp10) of Cyprinus carpio, in silico approach

open access: yesЖивотновъдни науки, 2022
Fatty acid binding proteins (FABPs) belong to a multigene family of intracellular lipid binding proteins. The aim of the study was to identify the structure and properties of fatty acid binding protein from the liver of Cyrpinus carpio.
Anila Hoda, Valbona Kolaneci
doaj  

In-Silico Approaches for Molecular Characterization, Structural Function Prediction and Peptide Toxicity Analysis of the Matrix Protein of Vesicular stomatitis Indiana Virus (VSIV) [PDF]

open access: yesBIO Web of Conferences
Vesicular Stomatitis Indiana Virus (VSIV) is a primary RNA virus studied for its effects in virology and in biotechnology the matrix protein of VSIV is key in linking the viral envelope to the core which is essential role in the assembly and release of ...
S Ramya   +3 more
doaj   +1 more source

Molecular modelling and Function Prediction of hABH7, human homologue of _E. coli_ ALKB7 [PDF]

open access: yes, 2011
Human homologues of ALKB protein have shown the prime role in DNA damaging drugs, used for cancer therapy. Little is known about structure and function of hABH7, one of the members of this superfamily. Therefore, in the present study we intend to predict
Ambarish Sharan Vidyarthi   +2 more
core   +1 more source

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