Results 51 to 60 of about 180,875 (351)
Biomolecules, 2022 Heme proteins serve diverse and pivotal biological functions. Therefore, clarifying the mechanisms of these diverse functions of heme is a crucial scientific topic. Distortion of heme porphyrin is one of the key factors regulating the chemical properties
Hiroko X. Kondo +5 more
doaj +1 more source
Les mécanismes de repliement des protéines solubles [PDF]
Biotechnologie, Agronomie, Société et Environnement, 2000 Mechanisms of folding of soluble proteins. The function of a protein is carried out by its three-dimensional structure. The rules for translation of the information encoded by DNAinto an amino acid sequence are well known.
Brasseur B., Benhabilès N., Thomas A.
doaj
Development and Validation of Optimization Methods for the Design of Protein Sequences and Combinatorial Libraries [PDF]
, 2009 To facilitate the design of protein sequences with desired properties, simulation techniques have been developed to allow large portions of amino acid sequence space to be evaluated by computer.
Allen, Benjamin Daniel
core +1 more source
An Algebro-topological description of protein domain structure. [PDF]
PLoS ONE, 2011 The space of possible protein structures appears vast and continuous, and the relationship between primary, secondary and tertiary structure levels is complex.
Robert Clark Penner +3 more
doaj +1 more source
Bioinformatics Analysis of the NOT5 Gene in Saccharomyces uvarum
Shipin gongye ke-ji, 2022 Objective: In this paper, we obtained the NOT5 gene from Saccharomyces uvarum by transcriptome analysis. Analysis of its biological information can lay the foundation for the later study of the role of the gene.
Shujin DING +5 more
doaj +1 more source
Microbial Cell Factories, 2022 Background Native-like secondary structures and biological activity have been described for proteins in inclusion bodies (IBs). Tertiary structure analysis, however, is hampered due to the necessity of mild solubilization conditions.
Rosa Maria Chura-Chambi +2 more
doaj +1 more source
Flexible protein folding by ant colony optimization [PDF]
, 2008 Protein structure prediction is one of the most challenging topics in bioinformatics. As the protein structure is found to be closely related to its functions, predicting the folding structure of a protein to judge its functions is meaningful to the ...
Hu, X., Li, Y., Zhang, J.
core +1 more source
Analytical Chemistry, 2018 In recent years mass spectrometry-based covalent labeling techniques such as hydroxyl radical footprinting (HRF) have emerged as valuable structural biology techniques yielding information on protein tertiary structure.
Melanie L. Aprahamian +3 more
semanticscholar +1 more source
Protein-Ligand Interactions: Docking, Design and Conformation Change [PDF]
, 2003 Virtual ligand screening has proven to be a successful strategy in drug design. An in house-developed procedure (HierDock), a coarse grain docking method followed by a fine grain search procedure, was used to determine the binding site for sugars in the
Datta, Deepshikha
core +1 more source
Computational and Structural Biotechnology Journal, 2021 Defensins are small proteins, usually ranging from 3 to 6 kDa, amphipathic, disulfide-rich, and with a small or even absent hydrophobic core. Since a hydrophobic core is generally found in globular proteins that fold in an aqueous solvent, the peculiar ...
Mariana H. Moreira +3 more
doaj +1 more source