Results 151 to 160 of about 1,386,749 (339)

Peptide binder design with inverse folding and protein structure prediction. [PDF]

Commun Chem, 2023
Bryant P, Elofsson A.
europepmc   +1 more source

N-Grams Modeling for Protein Secondary Structure Prediction: Exploring Local Features and Optimal CNN Parameters [PDF]

, 2023
Annisa Rizqiana, Afiahayati
openalex   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Protein structure prediction from the complementary science perspective. [PDF]

Biophys Rev, 2023
Vila JA.
europepmc   +1 more source

Species-specific protein secondary structure prediction

, 2010
Mariana Barssoum
openalex   +2 more sources

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Starting at Go: Protein structure prediction succumbs to machine learning. [PDF]

Proc Natl Acad Sci U S A, 2023
Rothman JE.
europepmc   +1 more source

ToGo-WF: prediction of RNA tertiary structures and RNA–RNA/protein interactions using the KNIME workflow [PDF]

, 2019
Satoshi Yamasaki, Takayuki Amemiya, Yukimitsu Yabuki, Katsuhisa Horimoto, Kazuhiko Fukui   +4 more
openalex   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Prediction of protein secondary structure by the improved TCN-BiLSTM-MHA model with knowledge distillation

Scientific Reports
Secondary structure prediction is a key step in understanding protein function and biological properties and is highly important in the fields of new drug development, disease treatment, bioengineering, etc.
Lufei Zhao, Jingyi Li, Weiqiang Zhan, Xuchu Jiang, Biao Zhang   +4 more
doaj   +1 more source