ABSTRACT Mutations in myelin regulatory factor (MYRF) are linked to demyelinating disorders. We report a 38‐year‐old male who developed acute symmetric leukoencephalopathy mimicking a stroke following an influenza A virus infection. While clinical symptoms markedly improved with corticosteroids, MRI revealed persistent white matter lesions, contrasting
Jinghan Hu +5 more
wiley +1 more source
Progress in AB Initio Protein Structure Prediction
David Baker
doaj +1 more source
Cloud Prediction of Protein Structure and Function with PredictProtein for Debian [PDF]
László Kaján +12 more
openalex +1 more source
Frailty Exacerbates Disability in Progressive Multiple Sclerosis
ABSTRACT Background To evaluate frailty in severe progressive multiple sclerosis (PMS) and to investigate the underlying mechanisms. Methods This prospective, cross‐sectional, multicenter study enrolled a late severe PMS group requiring skilled nursing (n = 53) and an age, sex, and disease duration‐matched control PMS group (n = 53).
Taylor R. Wicks +10 more
wiley +1 more source
Highly accurate protein structure prediction-based virtual docking pipeline accelerating the identification of anti-schistosomal compounds. [PDF]
Cheng W +10 more
europepmc +1 more source
Protein Eight Secondary Structure Classes Prediction Using Artificial Neural Networks.
Hanan Hendy
openalex +1 more source
Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
Advancements in one-dimensional protein structure prediction using machine learning and deep learning. [PDF]
Alanazi W, Meng D, Pollastri G.
europepmc +1 more source
DeepFold: enhancing protein structure prediction through optimized loss functions, improved template features, and re-optimized energy function. [PDF]
Lee JW +18 more
europepmc +1 more source

