Results 21 to 30 of about 417,581 (263)
BMC Bioinformatics, 2020 Background Whenever suitable template structures are not available, usage of fragment-based protein structure prediction becomes the only practical alternative as pure ab initio techniques require massive computational resources even for very small ...
Jad Abbass, Jean-Christophe Nebel
doaj +1 more source
Advances in protein tertiary structure prediction
Biomedical and Biotechnology Research Journal, 2018 Proteins are composed of linear chains of amino acids that form a unique three-dimensional structure in their native environment. Such native structure favors the proteins to perform their biochemical activity.
Tayebeh Farhadi
doaj +1 more source
Progress in protein structure prediction? [PDF]
Trends in Biochemical Sciences, 1993 Prediction of protein secondary structure is an old problem and progress has been slow. Recently, spectacular success has been claimed in the blind prediction of the catalytic subunit of the cAMP-dependent protein kinase. When predictions in this and other test cases are assessed critically, some claims of prediction success turn out to be exaggerated,
ROST, B. +2 more
openaire +3 more sources
Frontiers in Bioengineering and Biotechnology, 2022 Prediction of the protein secondary structure is a key issue in protein science. Protein secondary structure prediction (PSSP) aims to construct a function that can map the amino acid sequence into the secondary structure so that the protein secondary ...
Xin Jin +9 more
doaj +1 more source
ConformationLab studio: local AlphaFold2-based protein structure prediction on macOS using ColabFold
SoftwareXRecent advances in in silico protein structure prediction, particularly through AlphaFold, have enabled highly accurate modelling of proteins and their interactions.
Spike Murphy Müller
doaj +1 more source
Deep learning methods in protein structure prediction
Computational and Structural Biotechnology Journal, 2020 Protein Structure Prediction is a central topic in Structural Bioinformatics. Since the ’60s statistical methods, followed by increasingly complex Machine Learning and recently Deep Learning methods, have been employed to predict protein structural ...
Mirko Torrisi +2 more
doaj +1 more source
Protein 3D structure prediction Using Homology Method [PDF]
Fayoum University Journal of EngineeringFor decades, the prediction of protein three-dimensional structure from amino acid sequence has been a magnificent challenge problem in computational biophysics.
Rania Abul Seoud +2 more
doaj +1 more source
Accurate protein structure prediction with hydroxyl radical protein footprinting data
Nature Communications, 2021 Mass spectrometry-based covalent labeling techniques such as hydroxyl radical protein footprinting (HRPF) provide information about protein tertiary structures.
Sarah E. Biehn, Steffen Lindert
doaj +1 more source
PS4: a next-generation dataset for protein single-sequence secondary structure prediction
BioTechniques, 2023 Protein secondary structure prediction is a subproblem of protein folding. A light-weight algorithm capable of accurately predicting secondary structure from only the protein residue sequence could provide useful input for tertiary structure prediction ...
Omar Peracha
doaj +1 more source
Recent Progress of Protein Tertiary Structure Prediction
MoleculesThe prediction of three-dimensional (3D) protein structure from amino acid sequences has stood as a significant challenge in computational and structural bioinformatics for decades.
Qiqige Wuyun +7 more
doaj +1 more source